Category: Diseases & Conditions

  • Dr. Stephanie Efua Sobotie On Breaking Barriers And Building Sustainable Solutions

    Dr. Stephanie Efua Sobotie On Breaking Barriers And Building Sustainable Solutions

    Breaking down barriers in women’s healthcare remains a critical challenge in modern medicine, particularly in underserved communities. While urban centres often have multiple healthcare options, rural areas still need to improve their access to specialized medical care, especially in obstetrics and women’s health.

    The Alberta College of Family Physicians recently highlighted achievements in developing sustainable healthcare solutions with their Recognition of Excellence award, emphasizing the importance of effective approaches in bridging these healthcare gaps.

    Dr. Stephanie Efua Sobotie, recipient of this recognition, brings unique experience in developing healthcare solutions across diverse settings. From responding to critical needs in Ghana’s Kuntanase Government Hospital, where she established a blood bank after personally donating blood to save a patient’s life, to helping develop the obstetric program in Kindersley, Saskatchewan, her work demonstrates the impact of targeted healthcare initiatives.

    Now, as a family physician with a Certificate of Added Competence in obstetric surgical skills at Bow Trail Medical Clinic in Calgary and a clinical lecturer at the Cumming School of Medicine, she continues to address healthcare accessibility challenges. We sat down with Dr. Sobotie to explore what it takes to create compelling healthcare solutions and how connecting rural and urban healthcare experiences can improve medical care delivery.



    Image Courtesy of Dr. Stephanie Efua Sobotie


    Dr. Sobotie, as the first female physician in your family, what does ‘redefining women’s healthcare’ mean to you?

    When I consider redefining women’s healthcare, I envision creating a truly accessible system that addresses unique medical needs that have been historically overlooked. This vision was sparked early in my life when I noticed I could be the first woman physician in my family.

    At Bow Trail Medical Clinic in Calgary, we’ve built a women’s clinic that goes beyond primary care to address comprehensive health concerns throughout every life stage. But meaningful change requires reaching underserved communities, too. In Ghana’s Kuntanase Government Hospital, we established a program that successfully reduced maternal mortality rates in the Ashanti region. This work continued in Canada, where we’ve focused on bringing essential services to areas with limited healthcare access.

    Redefining healthcare also means preparing future generations of medical professionals. Through my role at the Cumming School of Medicine, I work to ensure that tomorrow’s healthcare providers understand the importance of advocating for women’s health needs and creating sustainable, accessible care systems.

    From Ghana to Canada, you’ve seen various challenges in medicine. In your opinion, what obstacles still exist for women in healthcare – both for doctors and patients?

    Based on my experience working across different healthcare systems, I’ve observed that access to specialized care remains a significant challenge, particularly in rural and underserved areas. This became evident during my time at Kuntanase Government Hospital, where we faced critical resource limitations – like not having a blood bank, which could have devastating consequences for women requiring emergency care.

    There are still barriers for women physicians in specific specialized fields. While I initially wanted to specialize in Trauma and orthopaedic surgery, my journey led me to family medicine, where I could make the most significant impact. However, I obtained additional qualifications, like my Certificate of Added Competence in obstetric surgical skills, to provide comprehensive care, especially in underserved areas.

    From my current perspective at the women’s clinic in Calgary, I see how these challenges manifest differently but persist even in well-resourced settings. Mental health support accessibility, for instance, remains a critical issue.

    I’ve witnessed firsthand how delays in accessing mental health services can have severe consequences for patients. These experiences have shaped my approach to creating more inclusive and comprehensive healthcare programs that address immediate medical needs and long-term wellness support.

    As part of Bow Trail Medical Clinic, you’ve helped establish a specialized women’s health division. What unique healthcare challenges are you aiming to address through this initiative?

    Through our women’s clinic in Calgary, we’re addressing several critical needs I’ve identified throughout my career. Working as a primary care physician in rural and urban settings, I’ve seen how crucial it is to provide comprehensive women’s healthcare beyond essential medical services.

    Our clinic focuses on providing continuous care throughout a woman’s life journey. Hospital privileges allow me to offer complete obstetric care, including surgical deliveries when necessary. This comprehensive approach is critical given my experience establishing obstetric programs from Ghana to Saskatchewan, where I’ve seen how integrated care can significantly improve outcomes.

    Additionally, based on my experience as a family physician with obstetric surgical skills, I recognized the need for specialized services that bridge the gap between primary care and specialized obstetrics. This is especially important as we aim to reduce barriers to accessing quality healthcare. We’re creating a model where women can receive coordinated care, from routine check-ups to more complex procedures, all within a familiar and supportive environment.”

    You received the Recognition of Excellence from the Alberta College of Family Physicians for contributing to family medicine. How does this experience help you create a more inclusive healthcare environment?

    Recognition of Excellence reinforced my commitment to building inclusive healthcare systems. This recognition reflects our success in implementing comprehensive care approaches that I’ve developed throughout my career. As a Family Practice Assessor for the College of Physicians and Surgeons of Alberta, I work to ensure high standards of care across diverse medical environments.

    This experience, combined with my clinical teaching at the Cumming School of Medicine, helps me promote inclusive practices among the next generation of physicians.

    You’ve created sustainable medical solutions in different settings, from establishing a blood bank in Kuntanase Hospital to developing the obstetric program in Kindersley. How do these projects help overcome systemic barriers to healthcare access?

    Each project emerged from real, urgent needs I witnessed firsthand. I’ll never forget that critical moment in Kuntanase when I had to donate my blood to save a patient with a ruptured ectopic pregnancy. That experience wasn’t just about saving one life – it revealed a systemic gap that needed addressing.

    Establishing the blood bank wasn’t just about creating a facility; it was about ensuring that no other woman would face that same life-threatening situation due to a lack of resources.

    In Kindersley, Saskatchewan, we faced different challenges but similar underlying issues of access to care. Developing the obstetric program there wasn’t just about adding services – it was about creating pathways for family physicians to gain advanced obstetric skills, ensuring sustainable care in rural communities.

    I’ve learned from working in these diverse settings that sustainable solutions must grow from local needs while maintaining consistent quality standards.

    These experiences taught me that overcoming healthcare barriers isn’t just about building facilities or programs – it’s about understanding community needs, training healthcare providers, and creating systems that can continue serving people long after initial implementation. Whether in Ghana or Canada, the principles remain the same:

    • Listen to the community.
    • Identify the critical gaps.
    • Build solutions that can stand the test of time.

    Your recent article in WJARR and upcoming publications in Arjonline explore essential aspects of women’s health. How does your research contribute to changing approaches in women’s healthcare?

    This research grew directly from my experience working with patients and seeing how physical Trauma during childbirth can have lasting effects on both mental and physical well-being. By publishing these findings, we’re helping to highlight the interconnected nature of women’s health issues.

    This is particularly important for healthcare providers in urban and rural settings, where understanding these connections can lead to better patient care. The research also supports what I’ve implemented in practice – the importance of considering both immediate medical needs and long-term well-being in women’s healthcare.

    These publications contribute to a growing body of evidence supporting more integrated approaches to women’s healthcare. These approaches move beyond treating isolated symptoms to understanding and addressing the full spectrum of women’s health needs.

    What healthcare barriers for women do you plan to overcome shortly?

    I want to help people who previously did not have access to high-quality medicine. Based on my experience from Ghana to Canada, I aim to continue developing sustainable healthcare programs in underserved communities, focusing on integrating mental health support with primary care services.

    Through my teaching roles at the Cumming School of Medicine and clinical practice, I’m committed to training the next generation of healthcare providers to understand and address the unique challenges women face in accessing comprehensive healthcare.

    Imagining medicine 10 years from now, what should a truly inclusive and sustainable healthcare system look like?

    A truly inclusive and sustainable healthcare system should combine the best elements I’ve seen work in different settings – from rural Ghana to urban Canada. It should ensure that every woman can access comprehensive care, regardless of location.

    This means integrating primary care with specialized services, particularly in underserved areas, while maintaining strong connections between community clinics and larger medical centres. Mental health support should be readily available, and healthcare providers should be trained to deliver culturally competent care. Most importantly, it should be a system that grows and adapts with its communities, ensuring long-term sustainability.

    Source link

  • Your Menopause Treatment Tablets Could Affect Heart Health: Here’s What Study Says

    Your Menopause Treatment Tablets Could Affect Heart Health: Here’s What Study Says

    Hormone tablets taken during menopause provide relief from symptoms, but do they have long-term health risks? Researchers have found that hormone replacement therapy (HRT) tablets containing both estrogen and progestogen may increase the risk of heart disease and blood clots in menopausal women.

    During menopause, women’s body goes through a series of changes due to a decrease in female hormones, progesterone, and estrogen resulting in symptoms such as hot flashes, mood swings, night sweats, insomnia, and vaginal dryness. These symptoms are often frustrating, interfering with their daily lives and mental well-being.

    HRT was once commonly prescribed for menopausal symptoms and to reduce the risk of bone loss during this stage. However, recent studies pointing to long-term risks have led to a more cautious approach. It is now recommended only for those where the benefits outweigh the risks. The estimate shows that only 5% of women in the U.S. use it now, a significant drop from about 27% two decades ago.

    The latest study published in The BMJ examined the effects of HRT tablets on heart health based on the route of administration and the combination of hormones used. The study suggests that tablets containing both estrogen and progesterone, such as oral combined continuous, oral combined sequential, oral unopposed estrogen, and transdermal combined therapy, increased the risk of ischemic heart disease and venous thromboembolism (blood clots) in women.

    The researchers also found that the tablet tibolone in particular was linked to a higher risk of heart disease, heart attack, and stroke, but not blood clots. Tibolone is a synthetic hormone that contains estrogen, progesterone, and testosterone.

    “Compared with not starting menopausal hormone therapy, starting oral combined continuous therapy or tibolone was associated with an increased risk of ischemic heart disease,” the news release stated.

    “If 1,000 women started each of these treatments and were observed for a year, we would expect to see seven new cases of venous thromboembolism across all groups,” the researchers wrote.

    However, there was no increased risk associated with transdermal treatments such as skin patches, gels, and creams.

    The researchers caution that the study does not prove that HRT causes heart health risks, as the findings are based on observational data. Also, the lack of information on menopausal status and other unmeasured factors, such as smoking and body mass index, may have influenced the results.

    Source link

  • Trump Pick for Public Health Chief Opposed COVID Lockdown, Wanted People to Get Infected on Purpose

    Trump Pick for Public Health Chief Opposed COVID Lockdown, Wanted People to Get Infected on Purpose

    President-elect Donald Trump‘s latest leadership pick for the National Institutes of Health once published an open letter slamming the COVID-19 lockdown, while promoting “herd immunity” as a solution to the pandemic.

    “Together, Jay and RFK Jr. will restore the NIH to a Gold Standard of Medical Research as they examine the underlying causes of, and solutions to, America’s biggest Health challenges, including our Crisis of Chronic Illness and Disease,” Trump wrote in a statement released Tuesday, AP News reported.

    Dr. Jay Bhattacharya, a professor of medicine, economic and health research policy at Stanford University whose research focuses not on the science of health but the economics of health care, was shadow-banned on Twitter after he joined in 2021 and started sharing misinformation regarding the pandemic, according to reporting by the Wall Street Journal. His account was fully reinstated after Elon Musk bought the platform and invited Bhattacharya to defend his output.

    During the COVID-19 pandemic, and before vaccines were available, Bhattacharya encouraged “low-risk” people to live normally to build immunity to the infectious disease while people at higher risk were protected in an open letter dubbed the Great Barrington Declaration, written by three medical experts, including Bhattacharya, in October 2020, AP News reported.

    At the time, then-NIH Director Dr. Francis Collins called the letter dangerous and “not mainstream science.”

    “I think the lockdowns were the single biggest public health mistake,” Bhattacharya later said during a panel discussion organized by Florida Gov. Ron DeSantis in March 2021.

    The Senate will have to approve Bhattacharya’s appointment before officially takes office.

    Originally published by Latin Times

    Source link

  • Vaping Affects Circulation With Immediate Effects, Study Finds

    Vaping Affects Circulation With Immediate Effects, Study Finds

    Vaping is often promoted as a safer alternative to cigarette smoking. But is using e-cigarettes truly risk-free? Researchers have discovered that vaping impacts circulation, with noticeable effects occurring immediately.

    In the latest study that will be presented at the annual meeting of the Radiological Society of North America (RSNA) next week, researchers explored the impact of both cigarette smoking and vaping on vascular function. The study found that while vaping exposes users to fewer toxic chemicals than cigarettes, it still affects circulation and overall health. Interestingly, the effect was observed even in e-cigarettes without nicotine.

    “E-cigarettes have long been marketed as a safer alternative to regular tobacco smoking. Some believe that e-cigarettes don’t contain any of the harmful products, such as free radicals, found in regular tobacco cigarettes, because no combustion is involved,” said Dr. Marianne Nabbout, the study lead author in a news release.

    To assess the impact on brain circulation, researchers evaluated 31 healthy participants—both smokers and vapers—using MRI scans before and after exposure to tobacco cigarettes, e-cigarette aerosol with nicotine, and e-cigarette aerosol without nicotine. The participants, aged 21 to 49, were compared to baseline scans from 10 non-smokers and non-vapers, aged 21 to 33.

    The study also measured blood flow speed in the femoral artery by placing a cuff on the upper thigh to restrict circulation. Also, the venous oxygen saturation of the participants, which shows the amount of oxygen in the blood returning to the heart after supplying oxygen to the body’s tissues was tested.

    After inhaling each type of vaping or smoking, blood flow in the superficial femoral artery significantly decreased. The greatest decrease in vascular function occurred after vaping e-cigarettes with nicotine, followed by those without nicotine. Vapers also showed lower venous oxygen saturation, indicating an immediate reduction in oxygen uptake by the lungs, regardless of nicotine content.

    “This study serves to highlight the acute effects smoking and vaping can have on a multitude of vascular beds in the human body. If the acute consumption of an e-cigarette can have an effect that is immediately manifested at the level of the vessels, it is conceivable that the chronic use can cause vascular disease,” Dr. Nabbout said.

    Source link

  • Miscarrying Texas Mother Becomes Latest Woman to Die As Doctors Risk 99-Year Prison Sentence for Administering Life-Saving Drug

    Miscarrying Texas Mother Becomes Latest Woman to Die As Doctors Risk 99-Year Prison Sentence for Administering Life-Saving Drug

    A Texas mother became the third woman to die as a result of the state’s abortion ban when legislation prevented a doctor from administering life-saving care.

    In June of 2023, 35-year-old Porsha Ngumezi suffered a miscarriage at just 11 weeks pregnant, causing her to lose an immense amount of blood. Ngumezi, who already had young children, had been “passing large clots the size of grapefruit,” according to nurse’s notes obtained by ProPublica.

    “You need a D&C,” Hope Ngumezi, Porsha’s husband, was told by his mother who was a former physician. A dilation and curettage, also referred to as a D&C, is a common procedure by which a doctor removes the remaining tissue from a uterus in order to allow the uterus to close up and stop bleeding. The procedure addresses first-trimester miscarriages and abortions.

    However, the obstetrician on duty, Dr. Andrew Ryan Davis, gave Porsha misoprostol, a drug intended to help her body pass the tissue independently instead of administering life-saving care due to hospital policy.

    The drugs were not enough to stop the bleeding, and Porsha eventually passed away.

    Porsha’s death could have been easily prevented by a simple medical procedure that has become intertwined in state abortion laws because it is sometimes used to enact first-trimester abortions. Texas state law demands a prison sentence of up to 99 years for any doctor who violates legislation.

    Porsha’s death is the fifth preventable death caused by a lack of access to a D&C in the first trimester or a dilation and evacuation in the second. Three of these deaths occurred in Texas, according to ProPublica.

    Instead of administering D&Cs, doctors are giving patients misoprostol instead as the drug is often used to induce labor and treat postpartum hemorrhage, making it less directly related to abortion. However, the drug is not recommended to treat unstable patients.

    “Stigma and fear are there for D&Cs in a way that they are not for misoprostol,” said Dr. Alison Goulding, an OB-GYN in Houston. “Doctors assume that a D&C is not standard in Texas anymore, even in cases where it should be recommended. People are afraid: They see D&C as abortion and abortion as illegal.”

    “All Houston Methodist hospitals follow all state laws,” said a spokesperson for Houston Methodist, “including the abortion law in place in Texas.”

    Originally published by Latin Times.

    Source link

  • New Chemical Identified In U.S. Tap Water, Scientists Urge Investigation Into Its Toxicity

    New Chemical Identified In U.S. Tap Water, Scientists Urge Investigation Into Its Toxicity

    Scientists have identified a new chemical byproduct in tap water consumed by millions of Americans, solving a decades-long mystery. This compound, formed during water purification with chloramine, raises health concerns for roughly 113 million people and warrants further investigation into its potential toxicity.

    Chloramine is a disinfectant created by combining chlorine with ammonia. It is preferred over chlorine in many water treatment systems due to its greater stability, which results in lower levels of disinfectant byproducts compared to chlorine.

    Although researchers first noted the unidentified chemical byproduct in tap water treated with chloramine nearly 40 years ago, its exact details were not known. In a recent study published in Science, scientists used advanced analytical methods to uncover its structure, which is now officially named chloronitramide anion.

    The researchers detected chloronitramide anion in all 40 samples taken from 10 drinking water systems located in seven states. It was not seen in ultrapure water, or drinking water treated without chlorine-based disinfectants.

    “It’s well recognized that when we disinfect drinking water, there is some toxicity that’s created. Chronic toxicity, really. A certain number of people may get cancer from drinking water over several decades. But we haven’t identified what chemicals are driving that toxicity. A major goal of our work is to identify these chemicals and the reaction pathways through which they form,” Julian Fairey, first co-author on the paper said in a news release.

    The study represents a significant breakthrough, as it successfully identified chloronitramide anion and determined its structure.

    “It’s a very stable chemical with a low molecular weight. It’s a very difficult chemical to find. The hardest part was identifying it and proving it was the structure we were saying it was,” Fairey noted.

    Although the toxicity of chloronitramide anion remains uncertain, researchers have raised concerns due to its widespread presence and structural similarities to other toxic compounds. They stress the need for further investigation by academics and regulatory agencies, such as the U.S. Environmental Protection Agency.

    “Even if it is not toxic, finding it can help us understand the pathways for how other compounds are formed, including toxins. If we know how something is formed, we can potentially control it,” Fairey added.

    Source link

  • Cardiovascular Fitness May Lower Dementia Risk, Even For Those With Genetic Predisposition, Study Finds

    Cardiovascular Fitness May Lower Dementia Risk, Even For Those With Genetic Predisposition, Study Finds

    Regular exercise is known to prevent chronic conditions and slow cognitive decline. New research suggests that cardiovascular fitness, the body’s ability to deliver oxygen to muscles during exercise, could also play a crucial role in reducing dementia risk.

    A recent study found that improved cardiorespiratory fitness is linked to better cognitive performance and a lower risk of dementia, even among those genetically predisposed.

    As people age, cardiovascular fitness typically declines by 3% to 6% every decade in their 20s and 30s. However, this decline accelerates to over 20% per decade once individuals reach their 70s. With reduced fitness, there is an increased risk of cardiovascular events such as strokes and heart attacks and mortality from all causes, according to the researchers of the latest study.

    The study evaluated 61,214 participants between the ages of 39 and 70 enrolled in the UK Biobank study between 2009 and 2010. The participants did not have dementia and were followed for up to 12 years.

    The researchers assessed the cardiorespiratory fitness of participants at the beginning of the study by conducting a 6-minute submaximal exercise test on a stationary bike. While neuropsychological tests were used to evaluate cognitive function, the participant’s genetic predisposition for dementia was estimated using the polygenic risk score.

    During the follow-up, 553 people were diagnosed with dementia. Based on the cardiorespiratory fitness scores, the participants were divided into three equal-sized groups standardized by age and sex.

    The analysis revealed that people with higher fitness scores were 40% less likely to develop dementia than those with lower scores. Also, dementia onset was delayed by nearly 1.5 years for those with high scores.

    The researchers noted that in those with a moderate to high genetic risk of dementia, high cardiovascular fitness reduced their risk of developing dementia by 35%.

    Since the study is observational, the researchers could not establish a direct cause-and-effect relationship. They noted some limitations, including the potential underestimation of dementia cases, as UK Biobank participants are healthier than the general population. Individuals with certain health conditions were excluded from the exercise test, making the study group healthier which may have impacted the findings.

    However, based on the current findings, the researchers suggest that “enhancing CRF could be a strategy for the prevention of dementia, even among people with a high genetic predisposition for Alzheimer’s disease.”

    Source link

  • Study Finds Two Common Gynecological Disorders Linked To Increased Risk Of Early Death

    Study Finds Two Common Gynecological Disorders Linked To Increased Risk Of Early Death

    History of two common gynecological disorders, endometriosis and uterine fibroids, is linked to an increased risk of early death, a recent study revealed.

    Endometriosis is a chronic reproductive disorder that affects about 10% of women of reproductive age. It occurs when tissue similar to the uterine lining grows outside the uterus, causing symptoms such as severe period pain, chronic pelvic pain, bloating, nausea, fatigue, and infertility. There is no permanent cure for the condition, so treatment involves managing symptoms.

    Fibroids are noncancerous growths on uterine walls that can cause symptoms such as heavy menstrual bleeding, back pain, and frequent urination. Around 40% to 80% of women have uterine fibroids.

    In a large-scale study, researchers analyzed 110,091 women from the Nurses’ Health Study II, aged 25-42 in 1989. The participants had no prior hysterectomy, cardiovascular diseases, or cancer. Diagnoses of endometriosis (via laparoscopy) and fibroids (via ultrasound or hysterectomy) were self-reported every two years from 1993.

    Over 30 years, there were 4,356 premature deaths, including 1,459 from cancer and 304 from cardiovascular diseases.

    The all-cause premature death rate for women with confirmed endometriosis was 2 per 1,000 person-years, compared to 1.4 per 1,000 for those without. After accounting for factors such as age, weight, diet quality, physical activity, and smoking status, individuals with endometriosis were 31% more likely to die prematurely (before age 70) compared to those without these disorders. The majority of these deaths were attributed to gynecological cancers.

    Although uterine fibroids were not linked to all-cause premature death, the condition elevated the risk of death due to gynecological cancers.

    “Women with a history of endometriosis and uterine fibroids might have an increased long-term risk of premature mortality extending beyond their reproductive lifespan,” the researchers concluded.

    “These conditions were also associated with an increased risk of death due to gynecological cancers. Endometriosis was associated with a greater risk of non-cancer mortality. These findings highlight the importance for primary care providers to consider these gynecological disorders in their assessment of women’s health,” they wrote in the study published in the journal BMJ.

    The researchers caution that since it is an observational study relying on self-reported data, it can be prone to errors. Also, as the participants were predominantly white healthcare workers, the findings may not be generalizable to other populations.

    Source link

  • Texas Woman Who Briefly Died After Rare Delivery Room Complication Has No Memory of Giving Birth to Triplets

    Texas Woman Who Briefly Died After Rare Delivery Room Complication Has No Memory of Giving Birth to Triplets

    A Texas woman retained no memory of giving birth to triplets, including the 48 to 72 hours leading up to the delivery, after being clinically dead for about 45 minutes post-birth.

    Tomball resident Marisa Christie gave birth to triplets in late August, during which she faced multiple pregnancy-related complications causing her to flatline multiple times in just 45 minutes.

    “It was the toughest moment of my life going from the most beautiful experience in seeing our baby girls for the first time to ‘oh my gosh my wife is—they’re doing CPR on her’. I just remember going to the restroom and collapsing on the ground expressing myself to God,” said her husband, Dylan Christie, who had been in the delivery room at the time of the births.

    Marisa, who had already had one son before giving birth to triplets, miraculously survived the ordeal. According to her Maternal Fetal Medicine Physician, Dr. Amber Samuel, Marisa survived a rare post-birth complication called amniotic fluid embolism, a condition with a mortality rate of 80%.

    “Some exposure that causes the mom’s body to react like a really bad allergic reaction. I think they call it like 7.7 cases on 100,000,” Dr. Samuel said.

    Dylan made the call for Marisa to be administered a hysterectomy, which ultimately saved her life. However, when she recovered and woke up, she had no recollection of the delivery or the days leading up to it.

    “My family took lots of photos and videos of me when I was in the hospital, which helped a lot to kind of have reality hit,” Marisa said.

    The family has set up a GoFundMe in order to cover Marisa’s medical costs.

    Originally published by Latin Times.

    Source link

  • Taking Pills For Cardiovascular Diseases? They May Also Protect Against Dementia, Study Says

    Taking Pills For Cardiovascular Diseases? They May Also Protect Against Dementia, Study Says

    Taking medications for cholesterol and blood pressure might seem like a health burden for many. But there’s good news for those who have to depend on cardiovascular medications. Researchers have found that beyond their cardiovascular benefits, long-term use of these drugs, especially when used in combination, may offer protection against dementia.

    The latest study conducted by Karolinska Institutet in Sweden revealed the use of common cardiovascular drugs for more than five years is associated with a reduced risk of dementia later in life.

    “Previous studies have focused on individual drugs and specific patient groups but in this study, we take a broader approach,” said Alexandra Wennberg, a lead author of the paper.

    The study analyzed dementia risk using data from Swedish national registers, involving around 88,000 individuals over the age of 70 who were diagnosed with dementia between 2011 and 2016. It also included 880,000 control participants. The researchers obtained data about the participants’ use of cardiovascular drugs from the Swedish Prescribed Drug Register.

    “The results show that long-term use of antihypertensive drugs, cholesterol-lowering drugs, diuretics, and blood-thinning drugs is associated with between 4 and 25 percent lower risk of dementia. Combinations of the drugs had stronger protective effects than if they were used alone,” the news release stated.

    However, the researchers noted that the use of antiplatelet drugs for stroke prevention may be associated with a higher risk of dementia. This could be due to the increased risk of microbleeds in the brain caused by these drugs, which are linked to cognitive decline.

    “The association between the use of common cardiovascular drugs and dementia risk suggests that these pathways may be explored for the development of dementia treatment though future research is necessary. Conversely, because antiplatelets are commonly used, it is important to further understand any long-term negative effects on cognitive outcomes.

    Researchers believe that the new finding adds an important piece of the puzzle for finding new treatments for dementia. Also, since the study observed cognitive decline associated with antiplatelet use, it highlights the need to consider their potential long-term cognitive effects when prescribing these medications.

    “We currently have no cure for dementia, so it’s important to find preventive measures,” said Wennberg.

    Source link