Tag: Health

  • Emerging gut health research | Dietitian Connection

    Emerging gut health research | Dietitian Connection


    Gut health is a hot topic in nutrition, and new research is reshaping how we think about the role of everyday foods in supporting the microbiome. In this episode, Associate Professor Jessica Biesiekierski unpacks the latest preliminary science on eggs and gut health. You’ll hear about surprising research findings on everyday foods, like eggs, and walk away with practical ways to apply this knowledge in patient care.

    Hosted by Brooke Delfino

    Biography

    Associate Professor Jessica Biesiekierski is Head of Human Nutrition at the University of Melbourne and an NHMRC Emerging Leadership Fellow. Her research explores how diet shapes gastrointestinal function and gut-brain interactions, spanning nutrient-specific investigations through whole-diet interventions and, most recently, egg-consumption trials. A recipient of the 2024 Rome Foundation Research Award and the Nutrition Society of Australia Mid-Career Research Award, Jess leads a multidisciplinary team advancing clinical and mechanistic nutrition studies.

    In this episode, we discuss:

    • How food influences gut health and the microbiome
    • Key nutrients for digestive health
    • The emerging science behind eggs and gut health
    • Short-chain fatty acids and the gut barrier
    • Evidence-based tips for communicating effectively with patients


    Additional resources

    • Sign up here for research updates and resources from Australian Eggs, shared straight to your inbox every two months.

    • Click here to connect with Jess on LinkedIn

     

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    The content, products and/or services referred to in this podcast are intended for Health Care Professionals only and are not, and are not intended to be, medical advice, which should be tailored to your individual circumstances. The content is for your information only, and we advise that you exercise your own judgement before deciding to use the information provided. Professional medical advice should be obtained before taking action. The reference to particular products and/or services in this episode does not constitute any form of endorsement. Please see  here  for terms and conditions.


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  • Extreme longevity and health optimization: What it really takes

    Extreme longevity and health optimization: What it really takes

    “I want to know I’m doing absolutely everything I can to preserve my health for as long as possible.”

    We hear this kind of thing a lot.

    People tell us they not only want to stay in good shape as they age, they also want to outlive their peers and age expectancies.

    Imagine you could maximize your healthspan and lifespan, fend off disease, and generally remain fit, lean, and youthful into your 90’s, 100’s, and then some.

    Sounds pretty compelling, doesn’t it?

    There’s just one problem: Common longevity advice seems to involve an extraordinary amount of effort. And time. And money. And complexity.

    Is all the effort necessary? Is it worth it?

    And, will it even work?

    In this article, we’ll explore:

    And, we’ll help you weigh the pros and cons so you can make informed decisions about your health, your body, and your life.

    The myths—and realities—of “optimizing” your health

    Health and longevity advice is everywhere these days: podcasts, books, social media, that guy at the gym…

    Plus, influential “figureheads” have given the movement outsized attention. Think: popular podcasters and health experts Dr. Peter Attia, Dr. Andrew Huberman, and Dr. Rhonda Patrick, and biohacker Bryan Johnson.

    We understand the appeal of this kind of content. Who doesn’t want a longer, healthier life? (Not to mention the comforting sense of control that can come from designing and executing a “perfect” health plan.)

    But for us at PN, where we’ve collectively coached hundreds of thousands of people with real human lives, we know that “optimal” is rarely realistic.

    Not only that, optimal isn’t necessary.

    Making modest, relatively consistent efforts towards health and well-being will likely give you better results than following an intense, highly “optimized” protocol.

    If that sounds hard to believe, we get it. So let’s explore that bold statement, starting with the biggest myths surrounding longevity and health optimization.

    Myth: The “basics” aren’t enough.

    There’s an idea that getting and staying healthy must require a set of complex, “cutting edge” strategies—especially if your goal is to outlive the average American.

    In reality, the “basics” work really, really well. (These are things like exercising regularly; eating a nutrient-rich diet; getting adequate sleep; managing stress; and staying socially connected. We’ll discuss these more later.)

    Only, very few people do the basics consistently.

    The real reason more people aren’t living as long, or as well, as they could be isn’t because they’re not taking ice baths or getting vitamin C infusions…

    It’s because they’re not doing the (relatively) simple stuff, consistently.

    If you’re really, truly doing a well-rounded set of health-promoting behaviors with 80-90 percent consistency, you’re probably already close to peak optimization.

    Myth: More is better

    If a handful of basic behaviors get results, then doing them perfectly and as much as possible will help you get, and stay, even healthier—right?

    Not so fast. There’s a law of diminishing returns when it comes to health and fitness efforts.

    Graph shows that with small amounts of health effort, longevity can improve a lot, but as those efforts increase, longevity benefits plateau

    Plus, in our experience, doing too many things or adding in too much complexity to your health and fitness regime can:

    • Add risk factors that could actually make your health and fitness worse (such as chronic injuries or burnout due to overtraining, and/or nutrient deficiencies or disordered eating due to an over-preoccupation with “clean” or restrictive eating).
    • Make it harder for you to sustain good habits. People who take on too much are more likely to burn out. Research shows people who try to accomplish multiple goals are less committed and less likely to succeed than those focused on a single goal.1
    • Make your life less enjoyable, which in turn compromises health. Striving to maximize physical health can interfere with mental, emotional, and social well-being, which plays an essential role in healthspan and lifespan. (One study showed people with high levels of happiness and life satisfaction lived up to 10 years longer than people with low levels.2)

    And what’s the point of living longer if you’re not living a full, well-rounded, enjoyable life? While some effort is definitely important, past a certain point, more isn’t necessarily better.

    Myth: Cutting-edge strategies offer significant benefits.

    Let’s say you could put all those advanced, complex strategies into action without sacrificing consistency or life enjoyment, or compromising your overall well-being.

    They’d have to pay off, wouldn’t they?

    Not necessarily.

    Much of the research on longevity optimization (so far) is either in mice, is observational, is theoretical, or has been tested on very small numbers of people for very short periods of time.

    In fact, many of the fringe methods and supplements touted by influencers or biohackers are not only unproven but even potentially unsafe.3 4 5 6

    Point being: Put your efforts towards foundational health behaviors with proven track records (the kind we’ll cover in this article) before you invest in fringe efforts.

    Myth: It’s all or nothing.

    You might think, “Well, I’m not getting out of bed at 5 a.m. five times a week to go running for 60 to 90 minutes to optimize my VO₂ max, so I may as well just accept I’m not going to be a healthy person.”

    Some folks feel overwhelmed by the idea of optimizing their health, so they figure they might as well do nothing.

    However, our internal data shows that you can be far from “perfect” to get results.

    In our year long PN Coaching program, even clients who practiced their (basic) habits less than half of the time got measurable results.

    10-49% consistency gets results; ALT TEXT: Graph shows men and women with 10 to 49 percent consistency still lost 11 pounds, 8 to 11 inches in girths, and 2 to 3 inches from waist

    (Read more: Nearly 1 million data points show what it REALLY takes to lose fat, get healthy, and change your body)

    Don’t let optimization culture convince you great health is beyond your capabilities.

    Instead, we encourage you to…

    • Consider your options. Review the facts, and get a clear understanding of which behaviors are most likely to give you the best bang for your buck.
    • Get clear on the tradeoffs. Decide which things you are, and aren’t willing to commit to.
    • Make decisions that align with your goals. Including what kind of lifestyle you want, and how you want to spend your time and dollars.

    Keep reading and we’ll guide you through it.

    The benefits—and tradeoffs—of a healthy lifestyle

    Putting effort towards your health is great. But efforts come with tradeoffs.

    Here’s a look at both the efforts, and the tradeoffs, to achieve the health you want for yourself.

    Large image shows six categories of health levels: coasting, light effort, medium, high, very high, and extreme. The medium and high categories offer the best “return on investment” in terms of effort and sacrifice versus overall health benefits.

    A deeper look: The most effective health behaviors (and their optimal dose)

    If you want to reduce your risk of chronic disease, and generally stay healthier for longer, what should you do?

    As we said earlier, the issue isn’t that we need some highly detailed, cutting-edge protocol. The basics work. The issue is that most people don’t do them.

    For example, as shown in the image below, most people don’t get enough fruits and veggies, sleep, or exercise. And the number of people who do all these things on a regular basis (while also avoiding tobacco and minimizing alcohol) is extremely low: likely a fraction of a percent.

    Graph shows only 10 percent of people eat 5 servings of fruits and veggies daily; 15 percent sleep 7 to 9 hours a night’ 24 percent get recommended weekly aerobic and resistance exercise; 71 percent drink moderately or less; and 89 percent don’t smoke

    Finally, let’s take a closer look at what these basics are, and the “sweet spot” of effort versus reward.

    Foundational Health Behavior #1: Exercise regularly

    All health experts agree: Moving your body is important.

    Yes, exercise will help you stay lean, and improve mood, energy, and function, but it will also help you stay alive (and healthier) for longer.

    In fact, a study of Harvard alumni found that any amount of physical activity reduces the risk of death from any cause. Exercise extended lifespan regardless of body weight, blood pressure, smoking habits, or genetic predisposition.7

    Another study of 272,550 older adults found engaging in even low amounts of physical activity significantly decreased risk of death from cancer, cardiovascular disease, and all causes.8

    Specifically, steep risk declines happened when accumulating at least 7.5 MET-hours* of activity per week. The greatest increase in benefits came from achieving 7.5 to 15 MET hours. Increasing activity beyond that further decreases risk, but at a continually lower rate, as the graph below shows.

    Graph show that cancer mortality, cardiovascular mortality, and all-cause mortality all decrease as exercise increases, with the greatest increase in benefits from achieving 7.5 to 15 MET hours of exercise per week

    *MET-hours (Metabolic Equivalent Hours) measures the energy cost of activity, based on duration and intensity. Some examples: 2 hours of resting = ~2 MET-hours; 2 hours of moderate-intensity aerobic activity = ~8 MET-hours; 2 hours of moderate resistance training = ~7 MET-hours.

    Increasing the intensity of exercise is an efficient way to rack up MET-hours, but plain old walking counts too: In a study of 28,000 adults, every 1,000 daily step increase was associated with a 12 percent lower risk of death. (This association began at 2,500 steps and continued up to 17,000 steps.)9

    (Cool factoid: For folks concerned with dementia in particular, one study showed that getting just 3,826 steps per day was associated with a 25 percent reduced risk of dementia—and getting 9,826 steps per day was associated with a 50 percent lower risk!10)

    Ideally, cardiovascular activity is paired with resistance or weight-bearing exercise.

    Resistance training supports health and longevity in various ways: it can help preserve valuable muscle mass, maintain mental sharpness, improve odds of surviving cancer, support metabolic health, and generally help you stay alive.11

    Among older adults especially, falls are a leading cause of death.12 Resistance training can both prevent the risk of falls–because of improved balance and muscle stability13—as well as reduce the risk of serious injury–because of better bone density.14Image shows how resistance training and aerobic training benefit numerous areas of health, such as cognitive function, blood sugar regulation, mobility, and more.

    A sedentary lifestyle does the opposite, increasing risk of cardiovascular disease, diabetes, hypertension, cancer (breast, colon, colorectal, endometrial, and epithelial ovarian cancer), and all-cause mortality.15

    In fact, two decades of sedentary lifestyle is associated with twice the risk of premature death compared to being physically active.16

    ▶ How much exercise should you do?

    Standard exercise recommendations suggest:17

    • 150 minutes per week of moderate-intensity aerobic activity, or 75 minutes per week of vigorous aerobic activity (or some combination of both), plus
    • 2 sessions per week of resistance training, targeting most major muscle groups

    Getting up to 300 minutes per week of moderate-intensity or 150 minutes of vigorous-intensity aerobic activity (or some mix of both) as well as three resistance training sessions per week provides further benefits.

    ▶ Are people getting enough exercise?

    Most people are not.

    Only 24 percent meet the recommendations for both aerobic and resistance exercise. And fewer than 47 percent of American adults meet recommendations for aerobic physical activity.17

    ▶ Is getting more than the recommended amount better?

    For the most part yes, but past a certain point, more effort delivers less benefit—and potentially more risk.

    Overtraining (and/or under-recovering) can disrupt hormone levels, mess with sleep and mood, cause excess fatigue, chronically elevate your heart rate, cause injuries, and more.18 19 Extreme volumes of endurance exercise training may be detrimental for the heart, and increase risk of myocardial fibrosis, coronary artery calcification, and atrial fibrillation.20 21 22 23

    So, the benefits of exercise exist on a U-shaped curve. (This is known as the “Extreme Exercise Hypothesis,24 as seen in the image below.)

    Graph shows a u-shaped curve where health risks are highest when exercise is either very low or extremely high, with the least risks at moderate or high exercise.

    A “high” amount of exercise is good for you, but the “highest” amount possible probably isn’t. (Health benefits likely max out around 7-10 hours of cardio, and 3-4 resistance training sessions per week.)

    We like what one study concluded: “If the mantra ‘exercise is medicine’ is embraced, underdosing and overdosing are possible.”25

    Foundational Health Behavior #2: Eat a nourishing, nutrient-rich diet

    Eating well doesn’t have to be complicated. There are a few key elements to nail down, and the rest is up to your own personal preferences and needs.

    We suggest focusing on three nutrition fundamentals.

    Nutritional key #1: Eat more whole and minimally-processed foods

    Whole and minimally-processed foods are naturally nutrient rich—complete with fiber, healthy fats, vitamins, minerals, and phytochemicals—and far less calorie-dense than highly- or ultra-processed foods (UPFs). They also have less sugar, sodium, and trans fats—the latter which is directly linked to an increased risk of cardiovascular disease, breast cancer, complications during pregnancy, colon cancer, diabetes, obesity, and allergy.26 27 28

    These qualities contribute to their many health benefits; Diets rich in whole or minimally-processed foods are associated with lower rates of depression,29 30 31 heart disease,32 type 2 diabetes,33 cancer,34 and improved longevity.35

    The largest study on processed foods—which included almost 10 million participants—found UPFs are linked to 32 harmful effects, including type 2 diabetes, mental health disorders, obesity, cardiovascular disease, and all-cause mortality.36

    Another study found that a higher consumption of ultra-processed foods (four or more servings daily) was associated with a 62 percent increased risk of all-cause mortality. (For each additional serving of ultra-processed food, all-cause mortality increased by 18 percent.)37

    Not that you need to be plucking tomatoes straight off the vine.

    Eating a minimally processed food diet is more about overall dietary patterns—and moving along the continuum of improvement—rather than rigidly avoiding all forms of processing.

    Illustrated table shows various foods types and their whole, minimally processed, or ultra-processed options. All foods exist on this continuum between whole and ultra-processed.

    ▶ How many minimally-processed foods should you eat?

    There currently aren’t any formal guidelines for the amount of minimally-processed foods to eat. In our experience coaching over 100,000 clients, we find people are most satisfied, and get significant health improvements, when 70 to 80 percent of their diet comes from whole or minimally-processed foods.

    Any improvement counts though. If you’re currently eating very few whole and minimally processed foods, getting at least 50 percent of your diet from these foods would make a big difference to your health, energy, and longevity.

    ▶ Are people eating enough minimally-processed foods?

    No.

    Recent US data shows that Americans get about 28.5 percent of their calories from whole or minimally-processed foods, and 56 percent of their calories from highly- or ultra-processed foods.38

    ▶ Is getting more than the recommended amount better?

    Not beyond a certain point.

    If you want to, consuming up to 90 percent of calories from minimally-processed foods will truly maximize your benefits, but beyond that there are likely no further benefits.

    Besides, some processed foods enhance health rather than detract from it. Think about the protein powder that helps you meet your protein requirements, the commercial salad dressing that helps you eat your vegetables, or the weekly brownie à la mode you share with your grandkid that brings joy to both of your lives.

    (Read more: What you should know about minimally-processed foods vs. highly-processed foods)

    Nutritional key #2: Eat five fruits and vegetables

    You’ve heard it a million times. We’ll be the nag and say it again: Eat your fruits and veggies.

    A massive study involving over 1.8 million people showed that eating more fruits and vegetables was significantly associated with a decreased risk of death—with the benefits plateauing at five servings a day. People who ate five servings a day had a 13 percent lower risk of death from any cause compared to people who ate two servings per day.39

    Additionally, the consumption of fruits and vegetables very likely reduces the risk of hypertension, coronary heart disease, and stroke; probably reduces the risk of cancer; and possibly prevents weight gain.40

    ▶ How many fruits and vegetables should you eat?

    A healthy target is five fist-sized servings of fruits and vegetables daily. (Generally, we recommend dividing that into three servings of veggies and two servings of fruit.)

    For bonus points, try to eat a variety of colors.

    The pigments in fruits and veggies come from various healthful nutrients (called phytochemicals or phytonutrients). Different colors mean different phytochemicals, giving you a diverse array of these beneficial compounds, which are likely responsible for a majority of the health benefits of fruits and vegetables.

    (Read more: What the colors of fruits and vegetables mean)

    ▶ Are people eating enough fruits and vegetables?

    No.

    Americans only eat an average of 2.5 servings of produce (fruit and vegetables combined) per day.41

    Only 12.2 percent of people meet fruit intake recommendations, and less—9.3 percent—meet vegetable intake recommendations.

    A mere ten percent of Americans get a full five servings of fruits and vegetables combined per day.42

    ▶ Is getting more than the recommended amount better?

    There are likely diminishing returns to eating more than the above suggestions.

    In that massive study mentioned earlier that observed 1.8 million people, the life-extending benefits of fruits and veggies plateaued at five servings per day.39

    In other words, higher intake (beyond two servings of fruit and three servings of vegetables) was not associated with additional disease risk reduction.

    That said, there may be other benefits to eating more fruits and vegetables. For example, due to their fiber and water content, fruits and vegetables are filling yet low in calories, so they can support weight management—and they certainly aren’t going to harm your health.

    Nutritional key #3: Eat enough protein

    Protein is the most important macronutrient to get right, especially as we age.

    Plant protein in particular is linked to a reduced risk of cardiovascular disease and death from all causes.43 44 45

    In terms of animal proteins, the results are more mixed. (That said, research on protein intake and mortality is generally based on observational studies that don’t give us clear ideas about cause and effect.) Generally, minimally processed forms of fish, poultry, and low-fat dairy are the best animal protein sources.

    To minimize health risks such as diabetes, cardiovascular disease, and cancer, limit processed forms of red meat (like bacon, hot dogs, deli slices, and pepperoni sticks). Even unprocessed forms of red meat should likely be limited to about 18 oz (~4 to 5 palm-sized portions) or less per week.46 47 48

    Nonetheless, regardless of the source, getting sufficient protein—at least 1.2 g of protein per kg of body weight—significantly reduces the risk for sarcopenia (muscle loss), frailty, and neuromuscular decline.49 50

    Protein is also vital for maintaining and building muscle, keeping bones and soft tissues healthy, supporting immunity, and more. It’s also the most satiating macronutrient, and thus helpful for fat loss and/or body recompositioning.

    ▶ How much protein should you eat?

    The current USDA recommendation for protein intake is at least 0.8 grams of protein per kg of body weight (0.35 g/lb). However, newer research suggests this is likely the absolute minimum amount, and only for relatively young sedentary individuals.

    A better minimum intake for most is likely 1.2 g/kg (0.55 g/lb, or about 3 to 5 palm-sized portions of protein-rich foods), especially for older adults, as they’re at greater risk of muscle loss.

    Protein intake for muscle growth and retention, and/or if performing resistance training or other vigorous exercise would be 1.6 to 2.2 g/kg (0.75-1 g/lb), or about 4 to 8 palm-sized portions of protein-rich foods.

    ▶ Are people eating enough protein?

    That depends on how “enough” is defined.

    Most adults eat at least 0.8 g/kg. However, up to 10 percent of young women and up to 46 percent of older adults don’t hit this mark.51 And, as noted, that recommendation is probably conservative compared to the ideal intake.

    Protein is also especially critical for those on GLP-1 medications (Ozempic, Wegovy, Zepbound) to help prevent the muscle loss they can lead to. Aiming for at least 1.2 g/kg is vital for this population, especially if they are also older. (Getting closer to 1.6 g/kg is even better, if possible.)

    ▶ Is getting more than the recommended amount better?

    Once you get up to 1.2 g/kg, not necessarily. That amount is likely adequate for most, especially sedentary folks.

    If you’re trying to build muscle and strength or recover from vigorous exercise, or are taking GLP-1 medication for fat loss, striving towards 1.6 g/kg would help you achieve that goal more easily.

    If you’re trying to maximize strength and muscle gains, and/or are doing lots of strenuous exercise, consuming 1.6-2.2 g/kg is optimal (with the highest end of that range maxing out all benefits).

    What about supplements?

    Supplements make up a large part of the discussion around aging, but in reality only play a small role when it comes to increasing health and longevity.

    Using supplements (like a multivitamin, or doctor recommended vitamin D or iron) to prevent or correct deficiencies can be helpful for overall health well-being.

    Then, there are other supplements that have reasonably strong track records and can help us meet nutritional needs (protein powder), improve performance (creatine), or potentially even slow aging (fish oil might slow biological aging by a small amount).52

    However, the buzziest, trendiest supplements are often less proven.

    For example, curcumin, spirulina, and ginger are often listed as supplements that might help with inflammation, a hallmark of aging. However, the research here is still early, and far from definitive.

    There are also even less substantiated supplements that might modify other aspects of aging (resveratrol, NAD+, NAC), but the evidence is either very minimal or only in animal models.

    Some supplements (especially herbal supplements) can even cause harm, like liver damage.53

    If you want to give supplements a try, check for high-quality third-party seals of approval from organizations such as NSF.

    Examine.com—an online database that provides independent research summaries and analyses on most popular supplements—is also an excellent resource to help you determine which supplements might actually be effective.

    Regardless, talk to your healthcare provider before taking supplements, particularly if you take other medication.

    Foundational Health Behavior #3: Get adequate sleep

    Research shows that men who get enough quality sleep live almost five years longer than men who don’t, and women who get enough live two and a half years longer.54

    Studies also show sleep is just as important for your heart health as exercise, whole foods, weight management, cholesterol, blood pressure, and blood sugar control.55

    Compared to 7 hours of sleep per day, a 1 hour decrease in sleep duration has been associated with an 11 percent increased risk of cardiovascular disease and a 9 percent increased risk of type 2 diabetes.56

    Older adults who sleep less than 6 hours per night are at higher risk for dementia and cognitive decline than those who sleep 7 to 8 hours.57 (Deep sleep helps clear beta-amyloid plaques and wash out toxins from our brain, thought to be partially responsible for dementia.)

    ▶ How much sleep should you get?

    Sleep experts agree that 7 to 9 hours a night on average—with at least 7 hours of sleep most nights of the week—is ideal for most.

    However, the exact ideal hours may vary person to person.

    Generally, the right amount of sleep for you is the amount that allows you to feel relatively refreshed shortly after waking up, and allows you to fall asleep relatively easily at bedtime, with relatively sustained energy throughout the day.

    ▶ Are people getting enough sleep?

    About a third of US adults don’t meet the recommended amount of 7 to 9 hours of sleep per night.58

    ▶ Is getting more than the recommended amount better?

    Not necessarily.

    It seems that 7 to 9 hours of sleep a night is ideal in terms of health outcomes.56

    Interestingly, longer sleep duration (over 9 hours per night on average) is associated with an increased risk of cardiovascular disease, type 2 diabetes, and overall mortality.59 60 61

    However, it’s not clear that these risks are caused by sleeping more. Just as likely, it may be other health problems (such as depression, sleep apnea, or heavy alcohol consumption) that lead to both longer sleep times and higher health risks.

    (Read more: Transform your sleep—The scientific way to energize your body, sharpen your mind, and stop hitting snooze)

    Foundational Health Behavior #4: Manage stress

    When left unchecked for long periods of time (say, months or years without periods of recovery), stress can have negative effects on nearly every aspect of our health, as the below image shows.

    Image shows the variety of effects chronic, unmanaged stress can have on the body, from brain fog, frequent infection, poor recovery, weight gain, and more.

    Chronic stress—which tends to increase heart rate, blood pressure, and inflammation—increases the risk of cardiovascular disease.62 63 64 Additionally, long-term stress tends to worsen mental and emotional health, increasing the risk of anxiety and depression.65 It can also make people more likely to turn to substances like alcohol as an attempt to cope.66

    That said… Not all stress is bad.

    In fact, stress is a normal, natural, and even beneficial part of life; the right amount helps us feel motivated, purposeful, and engaged with life.

    So, rather than avoiding or demonizing stress, it’s helpful to work with it, using it as an opportunity to develop healthy coping mechanisms, appropriate recovery strategies, and overall resilience.

    And this doesn’t necessarily mean sitting on a cushion and meditating.

    Stress management can include simple mindset shifts: Practicing self-compassion,67 having a growth mindset,68 and framing stress as a normal and even beneficial part of life69 have all been associated with better coping under stress.

    Basic self-regulation skills also help. This involves noticing and naming what you’re feeling, having good control over your actions, and using a broad range of coping skills to help yourself process emotions and recover from stress. With these skills, you build self-awareness and the ability to handle challenges better, because you know how to calm yourself down after an activating event—regardless of how it went.

    The below image offers a spectrum of more—small and big—ways to regulate stress.

    Image shows a continuum of options for stress management, ranging from 1 to 10 on an effort scale.

    ▶ How much stress management should you engage in?

    Think of stress management and recovery as a thing you do in proportion to the stress and demands of your life.

    We often use the analogy of a jug: When stress drains your tank, stress management and recovery practices help fill it back up again.

    Image shows a faucet pouring water into a jug next to a list of recovery practices. These are things that fill your recovery jug. There is also a faucet draining water out of the jug next to a list of stressors. These are things that drain your jug. The goal is to fill your jug as much as you are draining it.
    And, as with all of the foundational health habits we’ve discussed, every little bit counts.

    Whether you’re experiencing a little or a lot of stress in your life, even three to five minutes of purposeful recovery—doing deep breathing exercises, some journaling or gentle stretching, or just stepping outside to get some fresh air and listen to the birds—can help fill your tank.

    ▶ Are people doing enough to manage stress?

    Probably not.

    In the US, over a quarter of people report that most days, they’re so stressed they can’t function.70 In Canada, it’s similar: Just under a quarter of people say that most days in their life are either “quite a bit” or “extremely” stressful.71

    Additionally, over a third of people say they don’t know where to start when it comes to managing their stress.72

    ▶ Is getting more than the recommended amount better?

    Not necessarily.

    The goal is to find your stress “sweet spot.” Because we all enjoy and tolerate different types and amounts of stress, how you feel is actually a pretty good indicator of whether stress is too low, too high, or “just right.”

    As the image below shows, if you generally feel bored and purposeless, stress is likely too low; if you feel energized and engaged, stress is probably close to your “sweet spot”; and if you feel panicky or so overwhelmed you’ve started to feel hopeless, stress is likely too high.

    Image shows a continuum of stress. When stress is too low, we feel bored or purposeless. When stress is just right, we feel energized and engaged. When stress is too high, we feel anxious or numb.

    While having a routine for stress management is a smart idea, there’s likely a point of diminishing returns here too. If you’re in that stress “sweet spot” (energized/engaged, not bored and not overwhelmed), then adding more stress reduction techniques might not help further—and may actually add stress by giving you yet another task to do.

    Foundational Health Behavior #5: Stay socially connected

    You might not think of social connection as a health imperative, but it is.

    Not only is the social and emotional support associated with improved well-being, it’s also associated with reduced risk of premature death.73 74 When relationships are strong, people have a 50 percent increased likelihood of survival during any given time.75

    In fact, one of the longest running studies—the Study of Adult Development out of Harvard Medical School, which has been tracking participants for over 87 years (and counting)—found that strong relationships were the biggest predictor of not only life satisfaction but longevity. (Relationships were more predictive of these outcomes than social class, wealth, IQ, or genetics.)76

    No surprise, not having a social circle comes with its own distinct risks.

    Social isolation and loneliness can increase a person’s risk for heart disease and stroke, type 2 diabetes, depression and anxiety, suicidality and self-harm, dementia, and earlier death.77 78

    A frequently cited statistic highlights its profound impact:

    The effect of social isolation on mortality is comparable to smoking up to 15 cigarettes per day79—surpassing even the risks associated with obesity and physical inactivity.80

    ▶ Are people getting enough social connection?

    It seems many of us could use more friends.

    About 1 in 3 adults report feeling lonely, and 1 in 4 report not having social and emotional support.77

    Eight percent of adults say they have no close friends, 53 percent say they have between one and four close friends, and 38 percent report having five or more friends.81

    ▶ How much social connection should you aim for?

    Generally speaking, research finds that people who have three to five close friends they regularly interact with (one to three times per week, in-person or via phone call) get the most social benefit.82 83 84 85

    On average, interaction with a smaller group of people tends to provide more benefit than a large network of acquaintances.86

    That said, individual needs vary. If you feel authentically connected to others, have a strong sense of belonging, and generally feel socially fulfilled, that’s what matters most.

    ▶ Is getting more than the recommended amount better?

    Likely not. Some evidence suggests that excessive social engagement (daily or multiple times daily) actually might increase mortality risk.87 That’s probably because over-socializing can increase mental, emotional, and physical fatigue,88 and often this level of socialization includes alcohol or other potentially risky behaviors.

    Additionally, it can take away time and energy that could be put towards other life-building and health-promoting behaviors (like work, exercise, or sleep).

    The takeaway? Strive for socializing that brings value to your life. No need to add so much that you wind up exhausted, or unable to keep up with other priorities.

    Foundational Health Behavior #6: Minimize known harms

    Minimizing activities we know to be harmful is a key part of looking after your long-term health, yet it can be easy to overlook these things. (Maybe because we’d rather keep doing them.)

    Two of the biggest culprits are smoking and drinking alcohol.

    Harm Avoidance Key #1: Don’t Smoke

    We all know smoking is bad for us. But smoking is still relatively common:

    • In the US, 10.9 percent of adults smoke cigarettes, and 6.6 percent smoke e-cigarettes.89
    • Globally, the trend is even higher: 22.3 percent of the world’s population use tobacco (36.7 percent of men and 7.8 percent of women).90

    The WHO estimates more than 8 million people die prematurely yearly from tobacco use (with an additional 56,000 people dying annually from chewing tobacco).91 This makes tobacco a leading (i.e. top 3) risk factor for premature death and all-cause mortality.92

    Smoking is also a risk factor for several chronic conditions, including coronary heart disease, stroke, emphysema, and cancer.93 (Globally, about a quarter of cancer deaths are attributed to smoking.90)

    Harm avoidance key #2: Limit alcohol

    At this point, the research is pretty clear: Alcohol has negative implications for your health, especially past a certain point of regular use.

    Two graphs show that risk of cardiovascular disease and cancer increase a lot with heavy drinking, and a little with moderate drinking

    Alcohol plays a causal role in 200+ diseases, particularly liver diseases, heart diseases, at least seven types of cancers, depression, anxiety, alcohol use disorders, and dementia.94 95

    In 2019, 2.6 million deaths worldwide were attributable to alcohol consumption.96 For people in the 15-49 age range, alcohol is the leading risk factor for death, with 3.8 percent of female deaths and 12.2 percent of male deaths attributable to alcohol use.97

    ▶ How much alcohol is “safe” to drink?

    US guidance on alcohol suggests keeping intake at moderate levels, or less.98

    A moderate intake means:

    • Two drinks or less per day for men (14 or less per week), with no more than 4 at a single sitting
    • One drink or less per day for women (7 or less per week), with no more than 3 at a single sitting

    Importantly, a drink is defined as containing 14 grams (about 0.6 fluid ounces) of pure ethanol, which equates to:

    • 12 ounces of regular beer (5% alcohol by volume)
    • 5 ounces of table wine (12% alcohol by volume)
    • 1.5 ounces of 80-proof distilled spirits (40% alcohol by volume)

    ▶ Are people limiting their alcohol enough?

    In the US, people tend to drink more than the recommended guidelines.

    In 2021, the National Institute on Alcohol Abuse and Alcoholism reported that the average American aged 21 or older consumed 2.51 gallons of pure alcohol over the course of a year—equivalent to about 10 standard drinks/week.99 However, research suggests surveys typically underestimate consumption by 40 to 50 percent.100 Further, other research shows that the heavier a person drinks, the more significantly they’re likely to underestimate and/or underreport their drinking.101

    All that to say, the average American is likely having more (or even far more) than 10 drinks per week.

    Add to that:

    • In 2016, 36.4 percent of Americans (age 15+) said they had at least one episode of binge drinking (6+ drinks in one session) in the last month102
    • About 7 percent of the world’s population aged 15+ years have an alcohol use disorder96
    • Alcohol-related deaths have been rising: in the last five years, alcohol-induced deaths have increased by 26 percent103

    ▶ Is more abstinence from alcohol better?

    In 2023, the WHO released a statement saying no amount of alcohol is “safe.”104 This interpretation is still debated, and data continues to emerge.

    Here’s our take: An abstinence-only policy is likely a failed policy for many. Rather, we want people to be informed so they can make intentional decisions.

    To be clear, alcohol is not beneficial for physical health; it’s a known human carcinogen. However, while alcohol does increase health risks, risk does not rise in a linear fashion with intake. Meaning, small doses are unlikely to have a significant impact on your health. But when you drink more heavily, the risks rise exponentially.105

    Drinking heavily can mean either:

    • Having more than 7 drinks in a week for a woman, or more than 14 drinks in a week for a man, or
    • Having 4 or more drinks in one sitting for a woman, or 5 or more drinks in one sitting for a man (binge drinking).

    (Reminder: A single drink refers to those definitions mentioned previously. Pints of beer, and heavily poured wine glasses and cocktails are more than single servings… Just because it fits in a single glass doesn’t mean it counts as “one” drink.)

    Ultimately, it’s about finding the level of risk you’re willing to tolerate relative to whatever benefits you feel alcohol provides you.

    Our general recommendations:

    • If you’re otherwise healthy and have no other alcohol-related risk factors, limit drinking to moderate levels or less
    • If you’re otherwise healthy but have one or two alcohol-related risk factors (such as breast cancer history), limit drinking to light levels (1 to 3 or 4 drinks per week) with occasional moderate intakes on special occasions, or less
    • If you have several alcohol-related risk factors (such as breast cancer history, family history of alcoholism, or contraindicated medications) abstain from alcohol entirely

    Foundational Health Behavior #7: Do Basic Preventive Health Measures

    In all the chatter about longevity optimization, it can be easy to forget about all the boring—but no less important—things that help you stay safe and healthy throughout your life.

    These include things like:

    • Getting regular check-ups, or seeing your doctor or healthcare provider if questions or concerns arise
    • Getting recommended bloodwork, screenings, and vaccines
    • Getting and keeping blood cholesterol, sugar, and pressure in recommended ranges as early as possible
    • Regularly seeing your dentist, and regularly brushing and flossing
    • Practicing safer sex
    • Seeing medical specialists as recommended or appropriate (OBGYN, optometrist, ENT, dermatologist, etc.)
    • Wearing seatbelts (Buckling up in the front seat reduces risk of fatal injury by 45 percent!106)
    • Wearing a helmet when cycling, skateboarding, or motorbiking
    • Regularly wearing sunscreen (Used appropriately, sunscreen decreases risk of skin cancers by 40 to 50 percent107 108)
    • Protecting your hearing (Untreated hearing loss increases risks for depression, social isolation,109 110 cognitive decline,111 dementia,112 113 and falls114 115)

    … And generally using common sense. (As in, avoid the “hold my beer” type stuff.)

    Basic health maintenance and risk avoidance practices matter—a lot.

    Notably, we can’t control every element of our environment. Some factors influencing our health are more structural and systemic, woven into the fabric of our societies.

    These are called social determinants of health, and include poverty, racism, homophobia, lack of accommodation for disabilities, and displacement (as in the case of refugees). For some folks, doing the above protective behaviors—like visiting the family doctor, getting glasses, going to the dentist, or even walking safely down the street—will be harder, sometimes near impossible.

    This isn’t meant to be a throwaway line that diminishes the difficult reality for so many people, but rather a gritty, realistic mantra: Do the best you can with what you’ve got.

    ▶ How much preventative health care do you need to do?

    Generally speaking, aim to be consistent with the habits you know you “should” do.

    You know the drill: Brush and floss daily; wear your helmet every time you ride a bike; wear your seatbelt every time you drive; put on sunscreen when you go out into the midday sun; don’t regularly blast your music at full volume; and so on.

    And if you have lingering things on your “I should really do that” list (like getting that weird mole checked out, or that bloodwork done), go do it.

    ▶ Are people practicing enough basic preventative health measures?

    We’ve offered a long-ish list of basic health practices that can protect health, so we won’t go into each in-depth.

    That said, when looking at the above list, it’s probably fair to say most people will notice a few behaviors they might practice more consistently.

    For example, while most of us are really consistent with our seat belts (usage is close to 92 percent!116), many of us could break out the floss more often (only 32 percent of Americans floss daily117).

    And, research shows that only about half of cyclists and motorcyclists wear helmets when riding118 119 120 (and use is even lower among skateboarders and rollerbladers121).

    Hearing loss is the number one modifiable risk factor for dementia,122 so make sure you also follow the “60/60 rule” if you like to pump up the tunes on your headphones: Listen at 60 percent of your device’s maximum volume for 60 minutes, then take a break. (And wear earplugs when you mow the lawn!)

    ▶ Are more preventative measures better?

    Once again, there’s likely a law of diminishing returns when it comes to preventative health measures, just like everything else.

    The point isn’t to become obsessed with eliminating all possible risks at every turn.

    Rather, it’s that reasonable efforts towards protecting your health do count, and they‘re immeasurably more important for overall health than the latest optimization fads.

    Bonus Foundational Health Behavior: Foster a sense of purpose and meaning

    Research consistently shows that having a strong sense of purpose and meaning for our life improves our health, overall well-being, and longevity too.123

    A sense of purpose seems to help people live longer, even when controlling for other markers of psychological well-being.

    There’s something uniquely beneficial about having a strong purpose that’s different from, say, being happy.

    Having a strong sense of purpose can mean many things, but it generally indicates that you have goals, and an aim in life.

    This purpose can be many things:

    • Helping others
    • Being connected to family and/or close friends
    • Being a key part of a community
    • Enjoying a hobby
    • Learning new skills

    Having purpose may help with longevity for a few reasons:

    It makes you more likely to engage in health-promoting behaviors, such as getting enough sleep and eating more fruits and vegetables.123

    It also tends to improve mental health. For example, one study showed that people with the strongest sense of purpose had a 43 percent reduced risk of depression.123

    Finally, it may simply help people live longer because it makes you want to live longer. When people have a sense of purpose, they often want to live longer, healthier lives, so they can fulfill that purpose to its fullest. And while wanting to live won’t make it so, it certainly doesn’t hurt.

    Still thinking about optimizing? Consider these additional tradeoffs

    We hope it’s clear by now: You can take yourself really far with some solid basics (that will themselves take some decent time and effort!).

    But, if you want to go even further, your effort might have to increase exponentially, just as those gains become less certain, and more marginal.

    Here’s what to keep in mind.

    First, it takes a lot of time (and money) to optimize.

    Let’s compare the time and financial investment of two imaginary people.

    The first person is what you might call a “healthy” or “medium effort” person. They’re someone who is pretty consistently meeting all of the above recommendations.

    The second person is what you might call an “optimizer.” They do all the above recommendations, but to the max, and many of the fringe recommendations often discussed on health-related podcasts and books.

    How much time and money might each of these people invest in their health efforts on a weekly basis? Here’s what that might look like.

    Table compares various activities and costs of a regular healthy person and an “optimizer”. Generally, it takes 3 to 4 times the time and cost to “optimize” exercise, nutrition, and self-care activities.

    On top of that, there are “optimizing” behaviors and assessments that might be performed less often—say, monthly, seasonally, annually, or even every few years. Of course, these practices will still require time and money, so even though they’re less frequent, they still have to be accounted for.

    Here are some examples of those kinds of products, therapies, and tests:

    • Dietary supplements (vitamin, mineral, and/or herbal supplements; “superfoods”; fish oil; probiotics, resveratrol, NAD+, NAC, curcumin, & more)
    • Bloodwork testing (for advanced lipid testing, inflammatory markers, hormone levels, and nutrient status)
    • IV therapy (for hydration, vitamins, glutathione, or NAD+)
    • Infrared sauna sessions
    • Plasma transfusions
    • Gene therapy
    • Stem cell therapy
    • Medical tourism and therapeutics retreats
    • Full-body MRIs
    • Genetic testing
    • Concierge medical services
    • And more…

    Though it’s hard to estimate the cost of these items, opting to do just a handful could easily cost an extra $10,000+ per year.

    Overall, we’d estimate it takes at least three to four times the time, effort, and money to follow an “optimizer” type lifestyle, compared to a plain old “healthy” lifestyle.

    As we’ve seen above, this 3-4x effort will likely translate to some extra benefits, but the medium-effort “healthy” lifestyle will likely get most people at least 80 percent of the results they’re after (such as improved lifespan, healthspan, and quality of life).

    Besides, optimizing too much can negatively impact your well-being and quality of life.

    The harder and more extreme someone’s fitness or health regime, the harder they typically fall off the wagon. So, taking on too much can actually put you more at risk of quitting the foundational health behaviors we mentioned earlier.

    Even if you stick with it, over-focusing on health and longevity will almost certainly interfere with your ability to enjoy a full, well-rounded, meaningful life.

    For example, if you get too focused on physical health, you may find other aspects of your deep health and overall wellbeing suffer, such as your relational, existential, mental, and emotional health.

    Image shows that there are six domains of deep health: social, physical, existential, emotional, mental, and environmental.

    Take this a step further, and “optimizing” can tip over into obsession. Sometimes, under the surface of “I just really care about my health” is disordered eating, orthorexia, or another mental health condition.

    Graph shows that with small amounts of health effort, life satisfaction and overall well-being can improve a lot, but as those efforts increase, well-being benefits plateau

    This, to us, is the heart of things: It’s important to not only stay relatively healthy, but also to enjoy your life while you’re living it.

    In fact, enjoying your life isn’t separate from good health. It’s part of it.

    What to do next

    1. Clarify your goals.

    Take a step back and consider what you really want most for yourself.

    What kind of life do you want to have?

    How important is it to maximize your healthspan and lifespan, and how does that line up with your other priorities?

    2. Consider the tradeoffs.

    Given what you want most for yourself, and the resources you have available, what’s realistic for you?

    How much time, money, and effort are you willing to put in to achieve health and lifespan goals?

    What are you prepared to give up? What aren’t you prepared to give up?

    3. When looking to make improvements, start with the basics first.

    Review the foundational health behaviors in this article. How many of them are you already doing? Consistently?

    If you’re covering most of the basics, you might not need to do more. (Give yourself a pat on the back. You’re already elite!)

    Or, maybe there’s some room for improvement and you’d like to step it up a bit. Great! For the vast majority of people, improving any of these behaviors will deliver real, tangible results. Start with these, before chasing faddish, fringe, “super-optimal” stuff.

    4. Tune out the noise.

    Those people you hear on podcasts or social media aren’t the experts on you and your life.

    You get to decide what you want, and how to go about getting it.

    Be honest with yourself, and make choices aligned with what matters most to you.

    There’s plenty of advice out there, but remember: It’s your life. You get to make decisions that work for you.

    References

    Click here to view the information sources referenced in this article.

    If you’re a coach, or you want to be…


    You can help people build sustainable nutrition and lifestyle habits that will significantly improve their physical and mental health—while you make a great living doing what you love. We’ll show you how.


    If you’d like to learn more, consider the PN Level 1 Nutrition Coaching Certification. (You can enroll now at a big discount.)

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  • Chemical Safety, Cultivated Meat, and Our Health 

    Chemical Safety, Cultivated Meat, and Our Health 

    More than 95 percent of human exposure to industrial pollutants like dioxins and PCBs comes from fish, other meat, and dairy.

    By cultivating muscle meat directly, without associated organs like intestines, the incidence of foodborne diseases “could be significantly reduced,” as could exposure to antibiotics, “pesticides, arsenic, dioxins, and hormones associated with conventional meat.” Currently, the U.S. Food and Drug Administration has approved seven hormone drugs to bulk up the production of milk and meat. “In the European Union, there exists a total ban on such use,” however. Even without injected hormones, though, animal products naturally have hormones because they come from animals. “Eggs, example given, contribute more to the dietary intake of estradiol [estrogens] than beef, whether the animal is legally treated with hormones or not.” After all, eggs come straight from a hen’s ovaries, so, of course, they’re swimming with hormones. But if you’re directly growing just muscle meat or egg white protein, you don’t need to include reproductive organs, adrenal glands, or any of the associated hormones.

    “Chemical safety is another concern for meat produced under current production systems.” There are chemical toxicants and industrial pollutants that build up in the food chain, such as pesticides, PCBs, heavy metals, and flame retardants, but there is no food chain with cultivated meat. We could produce all the tuna we wanted, with zero mercury.

    When the World Health Organization determined that processed meat was a known human carcinogen and unprocessed meat a probable human carcinogen, it wasn’t even talking about the carcinogenic environmental pollutants. When researchers tested retail meat for the presence of “33 chemicals with calculated carcinogenic potential,” like polycyclic aromatic hydrocarbons (PAHs), organochlorine pesticides like DDT, and dioxin-like PCBs, they concluded that, in order to reduce the risk of cancer, we should limit beef, pork, or chicken consumption to a maximum of five servings a month.

    Why cultivate meat at all when you can just buy organic? Surprisingly, “consumption of organic meat does not diminish the carcinogenic potential associated with the intake of persistent organic pollutants (POPs).” A number of studies have recently compared the presence of environmental contaminants in organic meat versus conventional meat, and the researchers found, surprisingly, that organic meat was sometimes more contaminated. Not only organic beef either. Higher levels were also found in pork and poultry.

    If you look at the micropollutants and chemical residues in both organic and conventional meat, several environmental contaminants, including dioxins, PCBs, lead, and arsenic, were measured at significantly higher levels in the organic samples. As you can see below and at 2:56 in my video, The Human Health Effects of Cultivated Meat: Chemical Safety, the green is organic meat, and the blue is conventional. 

    Cooking helps to draw off some of the fat where the PCBs are concentrated, as shown here and at 3:01.

    Seafood seems to be an exception. Steaming, for example, generally increases contaminant levels, increasing contaminant exposure and concentrating mercury levels as much as 47 percent, as you can see here and at 3:15 in my video. Better not to have toxic buildup in the first place.

    More than 95 percent of human exposure to industrial pollutants like dioxins and PCBs comes from foods like meat, including fatty fish, and dairy, but the pollutants don’t appear magically. The only way the chicken, fish, and other meat lead to human exposure is because the animals themselves built up a lifetime of exposure in our polluted world, from incinerators, power plants, sewer sludge, and on and on, as you can see here and at 3:40 in my video.

    Unlike conventional meat production, a slaughter-free harvest would not only mean no more infected animals, but no more contaminated animals either. In terms of pollutants, it would be like taking a time machine back before the Industrial Revolution.

    Doctor’s Note:

    Cultivated meat means less contamination with fecal residues, toxic pollutants, antibiotics, and hormones; up to 99 percent less environmental impact; and zero pandemic risk. Cultivated meat allows people to have their meat and eat it, too, without affecting the rest of us.

    This is the final video in this cultivated meat series. If you missed the first two, check out the videos on Food Safety and Antibiotic Resistance.

    I previously did a video series on plant-based meats; see the related posts below.

    All videos in the plant-based meat series are also available in a digital download from a webinar I did. SeeThe Human Health Implications of Plant-Based and Cultivated Meat for Pandemic Prevention and Climate Mitigation.



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  • Antibiotic Resistance, Cultivated Meat, and Our Health 

    Antibiotic Resistance, Cultivated Meat, and Our Health 

    Medically important antibiotics are being squandered by animal agriculture to compensate for typical factory farming practices.

    Cultivating muscle meat directly from cells instead of raising and slaughtering animals would reduce the risk of foodborne illnesses “due to fecal contamination during slaughtering and evisceration of carcasses” because there would be no feces, no slaughter, and no carcasses to eviscerate. In addition, cultivating meat would also reduce the threat from antibiotic resistance.

    To compensate for overcrowded, stressful, and unhygienic conditions on factory farms, animals are typically dosed en masse with antibiotics. A lot of antibiotics. About 20 million pounds of medically important antibiotics a year, as you can see here and at 0:57 in my video, The Human Health Effects of Cultivated Meat: Antibiotic Resistance

    In the United States, for example, farm animals are given about 2 million pounds of penicillin drugs and 15 million pounds of tetracyclines annually. This is madness. 

    Antibiotic drugs important to human medicine go right into the feed and water of animals like cows, pigs, and chickens, by the ton and by the thousands of tons, as shown below and at 1:02 in my video. And that is all without a prescription.

    Ninety-seven percent of the tens of millions of pounds of antibiotics given to farm animals in the United States are bought over the counter—without a prescription or even an order from a veterinarian, as seen here and a 1:24. To get even a few milligrams of penicillin, we need a doctor’s prescription, because these are miracle wonder drugs that can’t be squandered. Meanwhile, farmers can just back their trucks up to the feedstore. 

    Now, half the Salmonella in retail meat—chicken, turkey, beef, and pork—is resistant to tetracycline, as shown below and at 1:50 in my video. About a quarter of the bugs are now resistant to three or more entire classes of antibiotics, including some resistant to “cephalosporins such as ceftriaxone [which] are critically important drugs we use to treat severe Salmonella infections, especially in children.” 

    Such agricultural applications for antimicrobials are now considered an “urgent threat to human health.” “The link between antibiotic use in animals and antibiotic resistance in humans is unequivocal.”

    As shown here and at 2:20 in my video, it all starts with the poop. 

    Antibiotic-resistant bugs are selected for and then can spread via meat or produce contaminated by poop or they can spread through the wind, the air, or the water, or be carried by insects. There are many pathways by which resistant superbugs can escape. So, even if you don’t eat meat, you can be “put at risk by the pathogens released from stressed, immunocompromised, contaminant-filled livestock” dosed with antibiotics. That’s one of the reasons the American Public Health Association called for a moratorium on factory farms, due in part to all the pollution from concentrated animal feed operations (CAFOs) to the surrounding communities. 

    Every year, more than five tons of animal manure are produced for every man, woman, and child in the United States. Again, it all starts with the poop. But cultivated meat means no guts, no poop, no fecal infections, and no antibiotics necessary. It also means no fecal or antibiotic residues left in “foodstuffs such as milk, egg, and meat” that can potentially cause a variety of side effects beyond just the transfer of antibiotic-resistant bacteria to humans.

    And, as you can see here and at 3:30 in my video, things are getting worse, not better. U.S. animal agriculture is using more antibiotics now than ever.

    This isn’t only because more animals are being raised for food, either. Antibiotic sales in the United States are outpacing meat production. Yes, meat production is going up, but there is a serious rise in antibiotic sales for meat production, as shown below and at 3:46.

    With the combined might of Big Ag and Big Pharma (who profit from selling all the drugs), it’s hard to imagine anything changing on the political side. The only hope may be a change in the production side.

    “The unstoppable rise of super-resistant strains of bacteria is a serious worldwide problem, resulting in 700 000 deaths every year,” and the projections for global antibiotic use in the production of farm animals are “ominous,” estimated to exceed 100,000 tons of antibiotics pumped into animals raised for food by 2030. Quite simply, we may be “on the path to untreatable infections” by using even some of our “last resort antibiotics,” like carbapenems, just to shave a few cents off a pound of meat.

    And it’s not just foodborne bacteria. Mad cow disease, swine flu, and bird flu have the potential to kill millions of people. Skeptical? I’ve got a book for you to read, whose author’s “superb storytelling ability makes every page of the book interesting and fascinating for both specialist and layperson.” (Thanks, Virology Journal, for the wonderful book review and calling my book “a must read.”)

    Given the threat of the chickens coming home to roost, an editorial in the American Journal of Public Health thought that “it is curious, therefore, that changing the way humans treat animals—most basically, ceasing to eat them or, at the very least, radically limiting the quantity of them that are eaten—is largely off the radar as a significant preventative measure. Such a change, if sufficiently adopted or imposed, could still reduce the chances of the much-feared influenza epidemic…Yet humanity does not consider this option.”

    That may be moot, though, because we could cultivate all the chicken we want, without guts or lungs.

    It’s hard to stress the importance of that American Journal of Public Health editorial. As devastating as COVID-19 has been, it may just be a dress rehearsal for an even greater threat waiting in the wings—the wings of chickens.

    According to the Centers for Disease Control and Prevention, the leading candidate for the next pandemic is a bird flu virus known as H7N9, which is a hundred times deadlier than COVID-19. Instead of 1 in 250 patients dying, H7N9 has killed 40 percent of the people it infects.

    The last time a bird flu virus jumped directly to humans and caused a pandemic, it triggered the deadliest plague in human history—the 1918 pandemic that killed 50 million people. That had a 2 percent death rate. What if we had a pandemic infecting billions where death was closer to a flip of a coin?

    The good news is that there is something we can do about it. Just as eliminating the exotic animal trade and live animal markets may go a long way toward preventing the next coronavirus pandemic, reforming the way we raise domestic animals for food may help forestall the next killer flu. The bottom line is that it’s not worth risking the lives of millions of people for the sake of cheaper chicken.

    If you missed the previous video, see The Human Health Effects of Cultivated Meat: Food Safety. Up next is The Human Health Effects of Cultivated Meat: Chemical Safety



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  • Long-Term Health Impacts of Common Car-Crash Injuries

    Long-Term Health Impacts of Common Car-Crash Injuries

    Car collisions are usually framed as single, dramatic events – a sudden screech of brakes, a jolt, a trip to the emergency room, and then a slow return to “normal.” Yet for many crash survivors, the story doesn’t end when they’re discharged. Lingering pain, neurological changes, and psychological scars can reshape daily life months or even years later. Understanding these hidden trajectories is crucial not only for victims but also for the medical professionals, insurers, and legal advocates who support them. If you or a loved one have been hurt in a wreck and are weighing your next steps, consulting a seasoned South Carolina personal injury attorney can help you secure the resources you’ll need for the long haul – because true recovery extends far beyond the initial hospital visit.

    Early intervention is just one piece of the puzzle. Ongoing diagnostics, physical therapy, and mental-health care often determine whether a patient regains full function or struggles with chronic disability. The following sections explore how six of the most common crash-related injuries can evolve over time, revealing why vigilant follow-up care – and, in many cases, timely legal action – can make or break a survivor’s future.

    Traumatic Brain Injuries Can Rewire a Life You Thought You Knew

    Even a so-called “mild” concussion can trigger a cascade of neurological changes that last well past the visible bruises. Swelling, microscopic tearing of brain tissue, and disrupted neurotransmitter activity may lead to headaches, memory lapses, and mood swings weeks after the accident. More severe TBIs introduce risks of post-traumatic epilepsy, sleep disorders, and personality alteration that can upend careers and relationships. What complicates matters is the brain’s deceptive resilience in the first few hours after trauma; CT scans can appear normal, giving patients false reassurance.

    Long-term monitoring by a neurologist, accompanied by neuropsychological testing, often uncovers subtle but significant deficits only later. Cognitive-behavioral therapy, medication management, and workplace accommodations become part of the recovery landscape. Without these supports – and the financial resources to pay for them – many survivors watch their earning power erode just as medical bills mount, illustrating why early legal claims are essential to fund sustained neurological care.

    Whiplash Is More Than a Sore Neck – It’s a Multisystem Domino Effect

    Whiplash injuries occur when the cervical spine whips back and forth in rapid succession, stretching ligaments and irritating nerve roots. While neck pain and stiffness are immediate red flags, delayed symptoms often include dizziness, tinnitus, and visual disturbances. Research shows that up to half of whiplash patients develop chronic pain syndromes within a year, partly because micro-tears in soft tissue heal with scar formation that limits mobility. Compensatory posture shifts can then cause secondary problems in the shoulders and lower back.

    Long-term treatment frequently involves a combination of physical therapy, myofascial release, and targeted exercise regimens that may last six months or more. Insurance adjusters sometimes dismiss whiplash as “minor,” yet the economic toll of lost productivity and persistent therapy sessions can rival that of more dramatic injuries, which is why meticulous medical documentation and legal advocacy are vital from day one.

    Spinal Cord Damage Rarely Stands Still; It Evolves With Time

    Whether complete or incomplete, spinal cord injuries change the body’s communication superhighway. Initial swelling often masks the full extent of neural disruption, which can evolve as inflammation subsides. Many patients experience an arc: early paralysis or paresis, partial return of function, and then a plateau that leaves residual weakness or sensory loss. Over years, muscle atrophy, bone demineralization, and autonomic dysreflexia can develop, heightening risks for fractures and cardiovascular complications.

    Even mildly damaged spinal pathways may produce neuropathic pain that resists traditional analgesics, requiring costly neuromodulation devices or inpatient pain-management programs. Adaptive equipment – wheelchairs, home modifications, vehicle lifts – needs periodic upgrades, adding recurring expenses that must be anticipated in any settlement or verdict. A comprehensive life-care plan created by rehabilitation specialists often becomes a linchpin in proving future damages during litigation.

    Hidden Internal Injuries Can Spark Chronic Illness Months Later

    Seat-belt bruises and air-bag abrasions may steal the spotlight, but internal organs can sustain forces that only manifest problems over time. Splenic or liver lacerations might appear “stable” on imaging yet leave micro-hemorrhages that scar and impair function. The same shearing forces that tear soft tissue can kink intestinal blood vessels, leading to ischemic bowel segments weeks later. Blunt cardiac trauma increases the likelihood of arrhythmias and can precipitate heart-failure symptoms long after discharge. Kidney contusions sometimes culminate in hypertension as damaged nephrons alter fluid balance.

    Because these sequelae surface gradually, victims must engage in diligent follow-up with internists who understand post-trauma syndromes. Unfortunately, insurers sometimes close claims before late-onset complications emerge, forcing patients to shoulder new rounds of testing and treatment alone unless their initial legal strategy anticipated such possibilities.

    Psychological Trauma Frequently Outlasts Physical Healing

    Post-traumatic stress disorder, driving phobias, and generalized anxiety are common yet underestimated repercussions of serious crashes. Nightmares, flashbacks, and hypervigilance can sabotage sleep patterns and interpersonal dynamics, leading to depression or substance misuse. Executive dysfunction – difficulty focusing, planning, or regulating emotions – may jeopardize employment, especially in high-stress occupations.

    Evidence-based therapies such as EMDR and cognitive-processing therapy can dramatically improve outcomes, but they require time, specialized clinicians, and sometimes medications that insurers label as elective if unaccompanied by obvious physical injuries. Securing compensation for mental-health care therefore hinges on early psychological evaluations and robust documentation that connects emotional symptoms directly to the crash event. When attorneys build these costs into a settlement demand, survivors stand a far better chance of resuming fulfilling lives.

    Soft-Tissue Damage Is the Silent Architect of Chronic Pain

    Ligaments, tendons, and fascia often sustain microscopic damage during collisions, an injury category that standard X-rays cannot detect. Over time, these tissues may stiffen and shorten, pulling joints out of alignment and spawning degenerative arthritis. Myofascial trigger points can send referred pain to distant body regions, confusing diagnoses and delaying effective treatment. Because soft-tissue injuries rarely require dramatic surgeries, insurers may undervalue them despite their potential to spawn lifelong discomfort and mobility restrictions.

    Long-term management might include regenerative injections such as platelet-rich plasma, specialized chiropractic care, or Pilates-based rehabilitation – services that fall outside many basic health-insurance plans. Without sufficient settlement funds, patients often forgo these therapies, exacerbating disability and driving up indirect costs such as missed workdays and reliance on opioid medications.

    The Road Ahead: Proactive Care and Informed Advocacy Pave the Best Path to Recovery

    Modern emergency medicine saves countless lives after car crashes, yet its triumphs can overshadow the quieter battle that begins when the hospital gown comes off. From subtle brain changes and ligament laxity to delayed organ dysfunction and PTSD, many injuries unfold in chapters, not headlines. Survivors who remain vigilant, seek specialized follow-up, and secure the financial means to cover long-term care often reclaim fuller, healthier futures. Those who underestimate the hidden trajectories of crash injuries risk chronic pain, emotional turmoil, and financial instability.

    Partnering early with experienced medical teams and a diligent South Carolina personal injury attorney ensures that every potential complication – physical or psychological – is accounted for in both treatment plans and compensation strategies. By recognizing the long timeline of recovery, crash victims can transform short-term survival into lasting well-being, proving that true healing begins only after stepping beyond the ER doors.

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  • From Burnout to Bliss: Simple Self-Care Habits to Improve Your Mental Health

    From Burnout to Bliss: Simple Self-Care Habits to Improve Your Mental Health

    Introduction

    In today’s fast-paced world, it’s easy to get caught up in the hustle and bustle of daily life and neglect our mental health. Burnout, anxiety, and depression are just a few of the many mental health issues that can arise when we don’t prioritize self-care. However, by incorporating simple self-care habits into our daily routine, we can improve our mental health and transform our lives from burnout to bliss. In this article, we’ll explore the importance of self-care, discuss simple self-care habits that can improve mental health, and provide tips on how to incorporate these habits into our daily lives.

    Understanding Burnout and Mental Health

    Burnout is a state of emotional, mental, and physical exhaustion caused by prolonged stress, overwork, and lack of balance in life. It can lead to anxiety, depression, and a host of other mental health issues if left unchecked. Mental health is just as important as physical health, and neglecting it can have serious consequences. According to the World Health Organization (WHO), mental health is "a state of well-being in which an individual realizes their own abilities, can cope with the normal stresses of life, can work productively, and is able to make a contribution to their community." By prioritizing self-care, we can improve our mental health, increase our resilience, and live a more fulfilling life.

    Simple Self-Care Habits to Improve Mental Health

    Incorporating self-care habits into our daily routine can seem daunting, but it’s easier than we think. Here are some simple self-care habits that can improve our mental health:

    • Mindfulness and meditation: Practicing mindfulness and meditation can help reduce stress, anxiety, and depression. Even just a few minutes a day can make a big difference.
    • Exercise: Exercise is a natural mood booster and can help reduce symptoms of anxiety and depression. Find an activity you enjoy, whether it’s walking, running, or dancing, and make it a part of your daily routine.
    • Connect with nature: Spending time in nature can help reduce stress and improve mood. Take a walk in a park, go for a hike, or simply sit outside and enjoy the fresh air.
    • Journaling: Writing down our thoughts and feelings can help process and release emotions. Try journaling for just a few minutes each day to see the benefits for yourself.
    • Social connection: Connecting with others is essential for our mental health. Make time for friends and family, join a club or group that aligns with your interests, or volunteer in your community.

    Prioritizing Self-Care

    Prioritizing self-care is essential for improving our mental health. Here are some tips on how to prioritize self-care:

    • Schedule it in: Treat self-care as a non-negotiable part of your daily routine, just like brushing your teeth or taking a shower.
    • Start small: Don’t try to make too many changes at once. Start with small, achievable goals, such as taking a few minutes each day to practice mindfulness or going for a short walk.
    • Be kind to yourself: Remember that self-care is not a luxury, it’s a necessity. Be kind to yourself and prioritize your own needs.
    • Make it enjoyable: Choose self-care activities that bring you joy and make you feel good. Whether it’s reading a book, taking a bath, or listening to music, make time for activities that nourish your mind, body, and soul.

    Overcoming Obstacles to Self-Care

    Despite our best intentions, we often face obstacles that prevent us from prioritizing self-care. Here are some common obstacles and tips on how to overcome them:

    • Lack of time: We often feel like we don’t have enough time for self-care, but the truth is, we can’t afford not to prioritize it. Start small and find ways to incorporate self-care into your daily routine, such as taking a few deep breaths during your morning commute or doing a quick meditation session during your lunch break.
    • Self-care guilt: We often feel guilty taking time for ourselves, especially if we have others who depend on us. Remember that self-care is not selfish, it’s essential. By prioritizing your own needs, you’ll be better equipped to care for others.
    • Financial constraints: Self-care doesn’t have to break the bank. Find free or low-cost activities that bring you joy, such as going for a walk, practicing yoga at home, or reading a book from the library.

    Building a Self-Care Routine

    Building a self-care routine takes time and intention, but it’s worth it. Here are some tips on how to build a self-care routine that works for you:

    • Experiment and find what works: Try different self-care activities and find what works for you. Everyone is unique, and what works for one person may not work for another.
    • Be consistent: Consistency is key when it comes to self-care. Try to prioritize self-care at the same time each day, such as first thing in the morning or before bed.
    • Make it a habit: Make self-care a non-negotiable part of your daily routine, just like brushing your teeth or taking a shower.
    • Review and adjust: Regularly review your self-care routine and make adjustments as needed. Life is constantly changing, and our self-care needs may change too.

    Conclusion

    In conclusion, prioritizing self-care is essential for improving our mental health and transforming our lives from burnout to bliss. By incorporating simple self-care habits into our daily routine, such as mindfulness and meditation, exercise, and social connection, we can reduce stress, anxiety, and depression, and increase our resilience and overall well-being. Remember to prioritize self-care, overcome obstacles, and build a routine that works for you. By taking care of ourselves, we’ll be better equipped to take care of others and live a more fulfilling life.

    FAQs

    Q: What is self-care, and why is it important?
    A: Self-care refers to the activities and practices that we engage in to take care of our physical, emotional, and mental health. Self-care is essential for improving our mental health, increasing our resilience, and living a more fulfilling life.
    Q: How do I prioritize self-care when I’m feeling overwhelmed?
    A: Start small and focus on one or two self-care activities that bring you joy and relaxation. Schedule self-care into your daily routine, and remember that it’s a non-negotiable part of taking care of yourself.
    Q: What if I don’t have time for self-care?
    A: Self-care doesn’t have to take a lot of time. Start with small, achievable goals, such as taking a few deep breaths during your morning commute or doing a quick meditation session during your lunch break.
    Q: Can self-care really improve my mental health?
    A: Yes, self-care can significantly improve our mental health. By reducing stress, anxiety, and depression, and increasing our resilience and overall well-being, self-care can transform our lives from burnout to bliss.
    Q: How do I know what self-care activities are right for me?
    A: Experiment and find what works for you. Try different self-care activities, such as mindfulness and meditation, exercise, and social connection, and pay attention to how they make you feel. Remember, everyone is unique, and what works for one person may not work for another.

  • Heart health in culturally diverse populations

    Heart health in culturally diverse populations


    In this Heart Week special, we’re joined by Dr Rebecca Luong – Accredited Practising Dietitian, Sports Dietitian and PhD-qualified expert in cardiometabolic health. With a passion for practical, culturally inclusive care, Rebecca shares real-world strategies for supporting heart health across diverse populations.

    Hosted by Brooke Delfino

    Biography

    Dr Rebecca Luong is an Accredited Practising Dietitian and Accredited Sports Dietitian, also known as The Cardiometabolic Dietitian and co-founder of Heartful Flavours. Rebecca worked in various areas of dietetics, including private practice, outpatient hospital, supermarket nutrition and community health, before completing a PhD in nutrition and cardiometabolic health. Her aim is to improve the heart and metabolic health of individuals globally through providing the best practical evidence-based nutrition solutions. Currently, she provides online consultations and launched heart-healthy Asian seasonings on a mission to eliminate excess sodium intake and support heart health. Rebecca was awarded the Dietitians Australia President’s Award for Innovation, 2024.

    In this episode, we discuss:

    • How heart disease risk presents across different cultural groups
    • Real case studies in cardiometabolic nutrition
    • How to adapt traditional food practices for heart health
    • Strategies for overcoming engagement and access barriers
    • Practical tips for flavourful, heart-smart meals


    Additional resources

    The content, products and/or services referred to in this podcast are intended for Health Care Professionals only and are not, and are not intended to be, medical advice, which should be tailored to your individual circumstances. The content is for your information only, and we advise that you exercise your own judgement before deciding to use the information provided. Professional medical advice should be obtained before taking action. The reference to particular products and/or services in this episode does not constitute any form of endorsement. Please see  here  for terms and conditions.


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  • Think You’re Too Young To Worry? Habits That May Harm Your Health By 30s

    Think You’re Too Young To Worry? Habits That May Harm Your Health By 30s

    Many people believe they have time to quit smoking, heavy drinking, or other unhealthy habits, but new research suggests the damage may start much earlier than expected. Although it’s never too late to change, researchers now caution that these vices could begin affecting your health as early as 36.

    For those who keep postponing their decision to take up a healthy lifestyle, the latest study published in the journal Annals of Medicine could be an eye-opener.

    “Non-communicable diseases such as heart disease and cancer cause almost three-quarters of deaths worldwide. But by following a healthy lifestyle, an individual can cut their risk of developing these illnesses and reduce their odds of an early death,” said lead author Dr Tiia Kekäläinen in a news release.

    Researchers tracked the physical and mental health of hundreds of people over more than 30 years and found how risky habits like smoking, heavy drinking, and lack of exercise can take a serious toll on their health, often earlier than one would expect.

    The analysis showed that people with all three unhealthy habits: smoking, heavy drinking, and inactivity, had significantly worse physical and mental health compared to those who avoided them altogether.

    When examined individually, each habit took a unique toll. While lack of exercise was strongly tied to poorer physical health, smoking was linked mainly to worse mental health and heavy drinking was associated with declines in both. The more shocking reveal was the health effects started showing by the time individuals reached their mid-30s.

    The study also noted that the more unhealthy habits people had — and the longer they held onto them — the worse their health became. Over time, these habits affected their mental well-being, poorer self-rated health, and a buildup of metabolic risk factors that can lead to chronic diseases.

    “Our findings highlight the importance of tackling risky health behaviors, such as smoking, heavy drinking and physical inactivity, as early as possible to prevent the damage they do to from building up over the years, culminating in poor mental and physical health later in later life,” said Dr Kekäläinen.

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  • Why a Platform Approach Outperforms Point Solutions with Pritesh Patel, COO of Andor Health

    Why a Platform Approach Outperforms Point Solutions with Pritesh Patel, COO of Andor Health

    As artificial intelligence (AI) continues to reshape industries, healthcare remains pivotal. While many health systems have attempted to implement AI through point solutions—single-use applications that address specific needs—these fragmented tools often fail to deliver lasting value. The real potential of AI lies in a platform approach, where a unified system can repurpose AI capabilities across multiple functions, streamlining care delivery and operational efficiency at scale.

    At the forefront of this transformation is Andor Health, whose AI-first ThinkAndor® platform eliminates the inefficiencies of point-based AI solutions. According to Pritesh Patel, Chief Operating Officer of Andor Health, by scaling across a healthcare system, ThinkAndor’s® AI enables organisations to extend its benefits beyond single-use cases, unlocking new opportunities in clinical workflow orchestration, ambient documentation and enhanced AI vision capabilities.

    Why Point Solutions Fall Short

    The healthcare industry has seen cycles of adopting and replacing fragmented technologies, which have struggled to provide sustainable ROI. Many health systems initially implemented healthcare applications as a point solution, only to realise that managing disparate systems created more complexity rather than reducing it. The advent of AI-based point solutions puts healthcare organisations in a similar place – implementing singular AI features rather than a platform for the last scale. This approach places systems in the same situation as before.

    A platform approach, on the other hand, allows AI-enhanced use cases to be systematically deployed across an entire health system, creating a framework for scale and innovation. Once AI is approved and implemented at scale, it can be responsibly repurposed for use cases, providing a centralised and unified agent that enhances efficiency across various functions.

    Beyond Single-Use: The Power of AI at Scale

    Rather than being confined to one-off applications, AI-first ThinkAndor® delivers enterprise-wide value by supporting diverse functions across the care continuum.

    Clinical Documentation (AI feature)

    Through automated ambient documentation, ThinkAndor® improves documentation efficiency by 47% across various nursing workflows. For an inpatient admission, the platform also reduces ~200 EHR clicks per patient admission and boosts overall staff productivity by 15%. By tripling nursing capacity, this AI-driven documentation system allows clinicians to spend more time on patient care than administrative tasks.

    Machine Learning & Care Coordination

    Leveraging machine learning, ThinkAndor® supports predictive modelling that goes beyond traditional tools. AI-powered models, such as those used to predict post-operative recovery outcomes (e.g., urinary continence and erectile function following robotic-assisted radical prostatectomy), demonstrate significant potential for personalised patient care without increased administrative burdens. In one study, AI-based ANN models achieved AUCs of 0.74 for potency and 0.68 for continence, outperforming other predictive models. These models provide clinicians with data-driven insights to better manage patient expectations and guide shared decision-making throughout the patient care journey.

    ThinkAndor® also integrates neural vision insights to support ambient observation without requiring health systems to invest in proprietary hardware or edge-based computing. By leveraging existing endpoints, the platform uses AI agents to continuously scan for key conditions such as bed availability, cleaning status, provider identification, hand washing, patient falls, elopement, and more—enabling proactive workflows and improved care team coordination. Furthermore, these use cases can be tethered to ancillary systems (EMR, CRM, HR), automatically allowing the data transfer and action to happen.

    By integrating responsible AI at the enterprise level, Andor Health enables health systems to scale AI adoption efficiently, improving operational effectiveness and patient outcomes.

    Sustainable Healthcare Through AI Innovation

    AI is not just a tool for improving efficiency—it is also a key driver of a sustainable future in healthcare. ThinkAndor® optimises care coordination, reduces administrative burden, and enables data-driven decision-making, all while ensuring compliance with regulatory standards.

    As health systems look to the future, embracing a platform approach over point solutions is critical.

    By leveraging an AI Infrastructure at scale, healthcare organisations can maximise impact, improve workforce efficiency, and ultimately enhance the quality of patient care in a meaningful and sustainable way – not just now but for decades to come.

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  • What Repeated Antibiotic Use Could Be Doing To Your Child’s Health

    What Repeated Antibiotic Use Could Be Doing To Your Child’s Health

    Antibiotics have long been hailed as life-saving medications, helping the body fight everything from mild colds to life-threatening infections like pneumonia. However, researchers now caution that repeated use of antibiotics, especially during early childhood, may come at a cost.

    In a new study published in the Journal of Infectious Diseases, researchers tried to investigate how antibiotic use might be connected to the development of chronic health conditions in children. To do this, they analyzed health records from more than one million babies in the United Kingdom, tracking diagnoses of various long-term pediatric conditions up to the age of 12.

    The researchers found that frequent antibiotic exposure in children could disrupt the delicate balance of gut microbes, setting the stage for a range of allergic conditions later in life, including asthma, food allergies, and hay fever. The study also noted a connection between antibiotic use and the risk for intellectual disabilities, but researchers cautioned that further studies are needed to confirm these associations.

    “Antibiotics play a critical role in combatting bacterial infections, but physicians should be judicious when prescribing antibiotics to children under 2, as frequent use may affect long-term health outcomes,” said Daniel Horton, the lead author of the study in a news release.

    However, the study also found that not all pediatric health conditions were linked to antibiotic use. For example, there was no significant association between antibiotics and the risk of developing autoimmune diseases like celiac disease, inflammatory bowel disease, or juvenile idiopathic arthritis. Similarly, the researchers found no strong links to neurodevelopmental conditions such as attention-deficit/hyperactivity disorder (ADHD) or autism spectrum disorder (ASD).

    The link between antibiotics use and health risk was also found to be course depended, meaning, more courses of antibiotics children took, the stronger the risk. Even when comparing siblings where one took antibiotics early and the other did not the results were similar, which makes the findings more reliable.

    “Antibiotics are important and sometimes life-saving medicines, but not all infections in young kids need to be treated with antibiotics. Parents should continue to consult with their children’s doctors on the best course of care,” said Horton, who is also an associate professor of pediatrics and epidemiology at Rutgers Robert Wood Johnson Medical School and Rutgers School of Public Health.

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