Source: National Institutes of Health –
Related MedlinePlus Pages: Anemia
Category: Family Health
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ClinicalTrials.gov: Anemia
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Infectious Arthritis – Bone, Joint, and Muscle Disorders
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Analysis and culture of joint fluid
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Blood tests
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Sometimes sputum, spinal fluid, and urine tests
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Sometimes x-rays, magnetic resonance imaging (MRI), or ultrasound
Doctors typically suspect the diagnosis of infectious arthritis in people who have severe or unexplained arthritis and in people who have other combinations of symptoms that are known to occur in people who have infectious arthritis.
Usually, a sample of joint fluid is removed with a needle (called joint aspiration, or arthrocentesis) as soon as possible. It is examined for an increased number of white blood cells and tested for bacteria and other organisms. The laboratory can usually grow and identify the infecting bacteria from the joint fluid (called a culture), unless the person has recently taken antibiotics. However, the bacteria that cause gonorrhea, Lyme disease, and syphilis are difficult to recover from joint fluid. If bacteria do grow in culture, the laboratory then tests which antibiotics would be effective.
A doctor usually does blood tests because bacteria causing joint infections often appear in the bloodstream. Sputum, spinal fluid, and urine may also be tested for bacteria to help determine the source of infection and determine whether the infection is anywhere else.
If doctors suspect the infectious arthritis is caused by gonococci, samples are also taken from the urethra, cervix, rectum, and throat. Tests for chlamydial infection of the genitals (another sexually transmitted infection) are also done because many people who have gonorrhea also have a chlamydial infection.
To determine the correct treatment, doctors may analyze the joint fluid f to detect the DNA of gonococci and mycobacteria.
Doctors may take x-rays of the affected joint to rule out other conditions. Doctors may do magnetic resonance imaging (MRI) if the joint cannot be easily examined or aspirated. MRI or ultrasonography is also done to identify accumulations of fluid or collections of pus (abscesses).
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ClinicalTrials.gov: Acute Gastroenteritis
Source: National Institutes of Health –
Related MedlinePlus Pages: Gastroenteritis -

Venous Thromboembolism – Deep Vein Thrombosis (DVT)
Most people can treat DVT with medicines at home. Sometimes, more serious blood clots require you to stay in the hospital for treatment.
Your healthcare provider will likely prescribe blood-thinning medicine to keep blood clots from getting larger and prevent a DVT from becoming a life-threatening pulmonary embolism. If you are unable to take blood thinners, other medicines or procedures can help. Learn more about treatments for DVT.
As you recover from DVT, talk to your provider about what you can do to stay healthy.
- Be aware of possible complications. A condition called post-thrombotic syndrome can develop following DVT. If you experience pain, itchiness, or swelling, tell your healthcare provider.
- Prevent a repeat DVT. Talk with your provider about your risk, get regular checkups, and take all medicines as prescribed to help lower your chance of having repeat blood clots.
- Make healthy lifestyle changes. Talk to your provider about changes you may need to make, including choosing heart-healthy foods, getting physically active, aiming for a healthy weight, and quitting smoking.
- Take care of your mental health. Anxiety, fear, and stress can be common after a blood clot. Reach out to your healthcare provider if you need support.
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ClinicalTrials.gov: Addison Disease
Source: National Institutes of Health –
Related MedlinePlus Pages: Addison Disease -

Oral Allergy Syndrome Symptoms, Diagnosis & Treatment
If you suffer from hay fever (allergic rhinitis) caused by pollen, your mouth or throat may become itchy after eating an apple or celery. This happens in up to 50 to 75% of adults allergic to birch tree pollen. This reaction occurs because the proteins found in some fruits and vegetables are very similar to those found in pollen. These proteins can confuse the immune system and cause an allergic reaction or make existing symptoms worse, which is referred to as cross-reactivity. In the case of pollen and foods, the result of cross-reactivity is called Oral Allergy Syndrome (OAS) also known as Pollen Food Allergy Syndrome (PFAS).
OAS is a form of a contact allergic reaction that occurs upon contact of the mouth and throat with raw fruits or vegetables. The most frequent symptoms of OAS include itchiness or swelling of the mouth, face, lip, tongue and throat. Symptoms usually appear immediately after eating raw fruits or vegetables, although in rare cases, the reaction can occur more than an hour later. OAS is generally considered to be a mild form of food allergy. Rarely, OAS can cause severe throat swelling leading to difficulty swallowing or breathing. In a person who is highly allergic, a systemic reaction, called anaphylaxis (an-a-fi-LAK-sis), may be caused by a pollen cross-reactive raw fruit or vegetable, but this is very uncommon. OAS can occur at any time of the year.
Although there is no definitive test for OAS, affected individuals often have a positive allergy skin test or blood test for specific pollen, along with a history of symptoms after ingestion of the suspected foods.
Different Reactions Based on Different Allergies
Some people report symptoms with only one food and others with many different fruits and vegetables. Some people report that only certain varieties of the fruit cause symptoms, for example specific apple varieties.In the case of OAS, individuals react to different foods based on what type of seasonal allergies they are affected by. For instance, if you are allergic to birch tree pollen, a primary airborne allergen responsible for symptoms in the springtime, you may have reactions triggered by pitted fruit or carrot. Even peanuts, almond, and hazelnut may cause mouth itching in those with birch pollen allergy. If mouth itching is noted with nuts, you should see an allergist /immunologist because mild mouth symptoms may signal a more serious allergic reaction to nuts. People with allergies to grasses may have a reaction to peaches, celery, tomatoes, melons (cantaloupe, watermelon and honeydew) and oranges. Those with reactions to ragweed might have symptoms when eating foods such as banana, cucumber, melon, and zucchini. This convenient table lists the possible pollen and plant food cross-reactivities.
Managing Your Symptoms
If you have symptoms of OAS, avoid eating these raw foods, especially during allergy season because in many patients, OAS worsens during the pollen season of the pollen in question. One way to reduce cross-reactions with food is to bake or microwave the food because high temperatures break down the proteins responsible for OAS. Eating canned food may also limit the reaction. And, peeling the food before eating may be helpful, as the offending protein is often concentrated in the skin.Some studies have shown that treatment with allergy shots can improve the symptoms of OAS.
You should talk to your physician if:
• Your OAS symptoms are causing significant throat discomfort;
• Your OAS symptoms are getting progressively worse;
• Your OAS symptoms are caused by cooked fruits and vegetables;
• Your OAS symptoms are caused by nuts;
• You develop systemic reactions after eating raw fruits or vegetables such as hives, vomiting or difficulty breathing.
Please note that this list is not exhaustive.Click here for a PDF version of the chart.
Find out more about allergic rhinitis or hay fever.
The AAAAI’s Find an Allergist / Immunologist service is a trusted resource to help you find a specialist close to home.
1/10/2024
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Irritable Bowel Syndrome
Irritable bowel syndrome, or IBS, is a chronic or reoccurring series of gastrointestinal symptoms that often causes distress for those who have it. IBS is associated with a group of symptoms that affect the large and small intestines. It is estimated that IBS affects 10% to 15% of adults worldwide. Though no specific cause is known, several factors may contribute to IBS, including genetics, certain mental health disorders, food sensitivities or intolerances, infection or a change in intestinal bacteria type or amount. Certain foods and stress may trigger symptoms; diet changes, stress management and a healthy, active lifestyle may help manage IBS.
Symptoms of IBS
Symptoms vary, but typically include one or more of the following:
- Abdominal pain
- Cramping
- Constipation or diarrhea
- Bloating
- Gassiness
Your doctor may order medical tests to rule out other causes of these symptoms.
IBS Triggers
People with irritable bowel syndrome have a sensitive intestinal tract in which stress and diet may play a role.
- Stress. The colon contains nerves that connect to the brain. For people with IBS, stress can stimulate spasms in the colon, causing discomfort and pain.
- Diet. Some people with IBS find symptoms worsen after eating large meals or high-fat foods. Specific foods also may trigger symptoms and can vary from person to person.
Changes for the Better
The best way to manage IBS can be highly individualized. It’s important to understand what may cause episodes of discomfort and then work to eliminate or minimize them. While medication, stress management and probiotics may help, eating habits also should be a focus, because they can have a significant impact. Some simple changes in the way you eat may offer relief and reduce future flare-ups.
- Establish regular eating habits. Eating your meals at the same time each day may help regulate your bowels.
- Eat small, frequent meals instead of large ones. This will ease the amount of food moving through your intestinal tract.
- Focus on a healthful eating pattern, including sources of dietary fiber. Try whole fruits, vegetables, beans and whole grains including rolled oats, brown rice and whole-wheat bread. Make changes slowly. Fiber helps move food through your intestine, but it takes time for your body to adjust to eating more. Adding too much too quickly may result in gas, bloating and cramping.
- Drink enough fluids. Fiber draws water from your body to move foods through your intestine. Without enough water and fluids, you may become constipated.
- Watch what you drink. Alcohol and caffeine can stimulate your intestines, which may cause diarrhea. Artificial sweeteners that contain sugar alcohols such as sorbitol, mannitol and xylitol may cause diarrhea too. Carbonated drinks can produce gas.
- Consider FODMAPs. Fermentable, oligosaccharides, disaccharides, monosaccharides and polyols — these short-chain carbohydrates are found naturally in many of the foods we eat. They may be poorly absorbed in the intestine by people with IBS. A registered dietitian nutritionist can help determine if there are high-FODMAP foods you may be sensitive to and if a modified eating pattern is right for you.
- Identify problem foods and eating habits. Recording your daily food intake in a food diary during flare-ups can help you figure out which foods contribute to IBS symptoms.
How an RDN Can Help
A registered dietitian nutritionist can help you manage irritable bowel syndrome by developing an individualized eating plan. An RDN will work with you to identify which foods and habits might cause you distress and review healthy eating strategies to help you manage your symptoms, along with other forms of treatment, if needed.
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Chronic Kidney Disease, Diabetes, and Heart Disease | Chronic Kidney Disease
About CKD, diabetes, and heart disease
The relationship between CKD, diabetes, and heart disease is one example of the ways our organs are connected. When one organ isn’t working properly, it can put stress on other organs, causing them to stop working properly as well.
Your body uses a hormone called insulin that moves sugars from the blood and into your body’s cells for energy. If someone has diabetes, they either don’t make enough insulin or can’t use the insulin well.
If someone has CKD, their kidneys don’t filter out toxins and waste from their blood as well as they should.
Heart disease refers to several types of heart conditions. The most common condition, coronary artery disease, leads to changes in blood flow to the heart. This can cause a heart attack.
Make the connection
So how are these three conditions connected? Risk factors for each condition are similar and include:
- High blood sugar.
- High blood pressure.
- Family history.
- Obesity.
- Unhealthy diet.
- Physical inactivity.
High blood sugar can slowly damage the kidneys. Over time, they may stop filtering blood as well as they should, leading to CKD. Approximately 1 in 3 U.S. adults with diabetes has CKD.
When the kidneys don’t work well, it puts stress on the heart. When someone has CKD, their heart needs to pump harder to get blood to the kidneys. This can lead to heart disease, the leading cause of death in the United States. Change in blood pressure is also a CKD complication that can lead to heart disease.
Tips to prevent or manage all three
The good news is that you can manage or prevent CKD, diabetes, and heart disease all at once. These five tips can help you get started:
Get active
Being active can help prevent or manage CKD, diabetes, and heart disease. Find an activity you like, start small, and get moving!
Choose healthy foods and drinks
This is an important way to give your body the fuel it needs to function properly. Adding more fruits and veggies to your plate can also help you keep a healthy weight. This is a great way to prevent or manage CKD, diabetes and heart disease.
Quit smoking
Quitting is one of the best things you can do for your health. It’ll help you prevent CKD, type 2 diabetes, and heart disease. It also helps to improve any of these conditions if you have them. You don’t have to do it alone! For support, visit I’m Ready To Quit.
Find out your risk for prediabetes
Know where you stand by taking this 1-minute prediabetes risk test. If your risk is high, talk to your doctor about taking action to prevent or delay type 2 diabetes. The lifestyle change program through CDC’s National Diabetes Prevention Program can help you build the healthy habits you need to succeed.
Get your annual flu shot
People with chronic diseases are more likely to have health complications if they catch the flu. These complications can worsen an existing condition and can even be fatal.
Protect your heart if you have CKD
Over time, CKD often gets worse and can lead to kidney failure. People with kidney failure will need regular dialysis (a treatment that filters the blood) or a kidney transplant to survive.
Heart disease is the most common cause of death for someone on dialysis. When your kidneys don’t function properly, the heart has to work harder to circulate blood. This may lead to high blood pressure and possibly heart disease.
Tips to help protect your heart and kidneys:
Choose foods that are healthiest for your heart and your kidneys. Ask your doctor for a referral to a dietitian to understand which foods and drinks are best for you. Learn more about dialysis and a healthy diet.
Get regular physical activity to help lower your blood pressure and improve your heart health. And remember that moving more doesn’t have to be strenuous. Some great ways to get active are gardening, yoga, or brisk walking around the block. Ask your doctor about which activities are best for you and if there are any you should avoid.
Manage your weight and blood sugar by changing your diet and activity routine. For extra help, you can work with a dietitian to create an eating plan that works for you and your kidneys.
When you prevent or manage one condition, you can help prevent or manage all three. -

When pain signals an emergency: Symptoms you should never ignore
Adapted from Pain Relief Without Drugs or Surgery, Medical Editor: Melissa L. Colbert, MD, Instructor in Physical Medicine and Rehabilitation, Harvard Medical School; Interim Medical Director, Spaulding Rehabilitation Outpatient Center.
Most pain can be managed without a trip to the doctor. A bruised knee, a pulled muscle — these can be treated at home with some combination of rest, ice, and heat. But some types of pain require immediate attention from trained medical personnel.
- Chest pain. Call 911 immediately. You may be having a heart attack or another serious medical event such as a pulmonary embolism (a blockage of an artery in the lung). Typical heart attack symptoms include heavy pressure or tightness in the chest; crushing pain that goes to the neck, the jaw, the left arm, or the back; and pain accompanied by shortness of breath, sweating, dizziness, or nausea.
- Pelvic pain. Severe new pelvic pain can be a sign of appendicitis or, in women, a ruptured ovarian cyst or an early ectopic pregnancy.
- Sudden severe headache. Get immediate care if you get a headache that is the worst you’ve ever experienced, or if the pain is accompanied by fever, vomiting, stiffness, seizures, a rash, visual disturbances, trouble speaking, or weakness. You could be having a stroke or have an infection of the brain such as meningitis. Also seek medical care after any head injury, which can cause a concussion or life-threatening swelling of the brain.
- Severe or persistent abdominal pain. If abdominal pain is severe, persists, or is accompanied by symptoms such as a fever, abdominal tenderness, or blood in the stool, you may have a serious medical problem (for example, appendicitis, diverticulitis, or pancreatitis) that requires immediate medical care.
- Eye pain. See an eye doctor for evaluation if you get hit directly in the eye, you have stabbing pain in the eye, your eye turns red along with pain, your vision is impaired, or you see sudden flashes of light. These symptoms can indicate a serious eye problem such as an infection, glaucoma, a detached retina, or inflammation inside the eye (iritis or uveitis).
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Cold versus heat for pain relief: How to use them safely and effectively
Adapted from Pain Relief Without Drugs or Surgery, Medical Editor: Melissa L. Colbert, MD, Instructor in Physical Medicine and Rehabilitation, Harvard Medical School; Interim Medical Director, Spaulding Rehabilitation Outpatient Center.
For certain types of injuries, the use of cold or heat may help dissipate pain. There isn’t an abundance of scientific data to support the use of cold and heat, but these two widely used methods, if applied safely, may complement other pain relief treatments.
Cold, in the form of cold packs or an ice massage (rubbing a painful area with an ice cube), is effective in the hours right after an injury. In addition to pain relief, the application of cold can decrease inflammation and muscle spasms and may help speed recovery from an injury. Cold is also often recommended for back pain and other types of chronic pain, and many people find it helpful.
After the swelling and redness have gone down — or as needed, in the case of chronic pain — heat may be more useful. Moist heat can raise pain thresholds and decrease muscle spasms in people suffering from osteoarthritis, according to limited data. And very small studies suggest that heat may be useful for treating tendinitis early on. Other trials suggest heat wraps may reduce back pain and disability.
How to use cold to relieve pain
Standard therapy for injuries such as a sprain or strain — an injury in which you have stretched or torn a ligament, tendon, or muscle — is the PRICE technique, which stands for protection, rest, ice, compression, and elevation. What this means is that you protect and rest the injured part, apply a cold pack to it, compress the injured area if possible with a bandage, and elevate it to reduce swelling. Cold packs are also used to help relieve headaches, foot pain, and longer-lasting conditions such as tendinitis and some kinds of back pain. Cold can also reduce swelling from inflamed joints in some forms of arthritis.
If you suffer a sudden sprain or strain, applying cold can reduce swelling by slowing cell activity, constricting blood vessels, and blocking the release of chemicals known as histamines. The application of cold can also decrease pain by numbing the area. An ice massage combines these benefits with the pain-reducing effects of gentle pressure applied to the injured tissue.
In cases of chronic pain, proactive use appears to be the most effective icing strategy. If you’re about to engage in an activity that could cause a flare-up, try applying cold before the activity as well as afterward. This practice creates a temporary distracting stimulus (cold) that intercepts pain signals before they are relayed to the brain, and it helps to retrain the way the brain perceives the chronic pain. For some people, the effects of cold application can last for minutes, while for others it can last hours.
To apply cold, use a store-bought cold pack kept in the freezer, a bag of frozen vegetables, or ice cubes in a sealed plastic bag. Do not put the cold pack or ice directly on the skin; wrap it in a towel or pillowcase first to avoid tissue injury. Apply cold for no more than 20 minutes at a time, four to eight times a day for the first two days after an injury. Once the acute phase of the injury has passed — usually within a couple of days — you can apply heat.
How to use heat to relieve pain
As many people with arthritis know, applying a warm moist towel to a sore joint or taking a warm shower or bath can temporarily relieve pain. Heat raises your pain threshold and relaxes muscles. The goal of most heat therapy is to increase tissue temperature by 9° to 12° F. Your heat source should not be uncomfortably hot: exposure to temperatures above 113° F may be painful, and above 122° F may burn your skin.
There are several ways to apply heat. Hot packs, heating pads, hot whirlpools, and heat lamps, for example, can warm up the skin, muscles, and other tissues to a depth of about an inch below the surface of the skin. Deep heat treatments performed by a physical therapist use other kinds of energy, most often ultrasound but sometimes shortwave or microwave electromagnetic energy, to generate heat in tissues about two inches below the surface.
Moist compresses, such as a warm damp towel, are more efficient in transferring heat to the body than dry electric heating pads. At home, put a moist towel in a plastic bag to make the heat last longer. You can also buy gel packs that can be warmed up in the microwave oven. Be careful not to make them too hot. The gel packs are convenient and easy to use, and they can also serve as cold packs if you put them in the freezer. Whether you use a pack hot or cold, do not place it directly on your skin. Wrap it in a towel or pillowcase.
Do not use heat on a swollen, red, or hot area, or an injury you have just sustained, as it can cause more inflammation.