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  • Pura Boost

    Pura Boost

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  • How to Beat Creative Blocks at Work

    How to Beat Creative Blocks at Work

    Hit a wall at work? This quick video shares one piece of advice to help you beat creative blocks and generate fresh ideas.

    It’s Monday afternoon and maybe that second cup of coffee isn’t getting your brain geared quite the way you expected it to (although maybe another three will be okay, according to a Harvard neuroscientist.)

    When you’ve hit a wall at work, this video from New York Magazine‘s Science of Us suggests it’s time to go into tinker-mode. Research on creative problem solving shows people don’t spend enough time in this phase. The solution? Keep at it. People come up with better solutions the longer they spend working on them.


    Tinkering is key—the brain has “leaky filters,” as science columnist Sharon Begley writes. When we give ourselves the time, disparate items can sift together to form new combinations: the essence of creativity. “Short of a personality or brain transplant, you can maximize your inherent creativity by sheer perseverance.”  

    “Original ideas tend to be remote,” Mark Runco, professor of creativity studies at the University of Georgia and founder of the Creativity Research Journal argues, which means that the first 10 uses of string you think of will likely be commonplace, but if you push yourself, the next 10 will include some quite creative ones.

    The upshot? When it comes to creative blocks, if original ideas come late in the creative process, he points out, we should give ourselves time and space to come up with those “remote” ideas—time for our leaky filters to allow notions that have never made each other’s acquaintance to come together and undergo a kind of alchemy.



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  • Parenting 101: Essential Tips for New Parents

    Parenting 101: Essential Tips for New Parents

    Introduction to Parenting 101

    Parenting is a journey that is both rewarding and challenging. As a new parent, it’s natural to feel overwhelmed by the sheer amount of information and advice available. However, with the right mindset and support, you can navigate the ups and downs of parenthood with confidence. In this article, we’ll cover the essential tips for new parents, from preparing for your baby’s arrival to establishing a daily routine, and everything in between.

    Preparing for Your Baby’s Arrival

    Before your baby arrives, it’s essential to prepare your home, your relationship, and yourself for the new addition. Here are some tips to get you started:

    • Create a safe sleep environment: Make sure your baby’s sleep space is safe and comfortable. This includes investing in a crib or bassinet that meets current safety standards, using a firm mattress, and keeping soft toys and blankets out of the crib.

    • Stock up on essentials: Diapers, onesies, and baby wipes are just a few of the many essentials you’ll need for your baby. Make a list and check it twice to ensure you have everything you need.

    • Take a parenting class: Parenting classes can provide you with valuable information and support as you prepare for your baby’s arrival. They can also give you the opportunity to connect with other expectant parents and build a community of support.

    • Prepare your relationship: Having a baby can put a strain on your relationship, so it’s essential to communicate with your partner and make time for each other. Schedule regular date nights and make an effort to stay connected.

    Establishing a Daily Routine

    Establishing a daily routine can help you and your baby feel more grounded and secure. Here are some tips for creating a daily routine:

    • Create a schedule: Plan out your day, including feeding times, nap times, and playtime. Be flexible, but also try to establish a consistent routine.

    • Prioritize self-care: Taking care of yourself is essential for being a good parent. Make time for activities that nourish your mind, body, and soul, such as exercise, meditation, or reading.

    • Get moving: Exercise is essential for both physical and mental health. Try to incorporate physical activity into your daily routine, such as taking a walk with your baby or doing a postnatal workout.

    • Ask for help: Don’t be afraid to ask for help when you need it. Whether it’s a family member, friend, or neighbor, having a support system can make all the difference.

    Feeding and Nutrition

    Feeding your baby can be a challenging but rewarding experience. Here are some tips for feeding and nutrition:

    • Breastfeeding: Breast milk is the best nutrition for your baby, and it’s essential to establish a good breastfeeding routine. If you’re having trouble breastfeeding, don’t hesitate to reach out to a lactation consultant for support.

    • Formula feeding: If you’re formula feeding, make sure to choose a high-quality formula that meets your baby’s nutritional needs. Always follow the instructions on the label, and never leave your baby alone with a bottle.

    • Solid foods: When introducing solid foods, start with single-ingredient purees and gradually introduce new foods. Always check with your pediatrician before introducing new foods, especially if your baby has a history of allergies.

    • Healthy snacks: As your baby gets older, it’s essential to provide healthy snacks to support their growth and development. Choose snacks that are low in sugar and salt, and high in nutrients.

    Sleep and Bedtime Routine

    Sleep is essential for both you and your baby. Here are some tips for establishing a bedtime routine:

    • Establish a bedtime routine: Develop a calming and predictable bedtime routine that includes activities like bath time, reading, and singing.

    • Create a sleep-friendly environment: Make sure your baby’s sleep space is dark, quiet, and at a comfortable temperature.

    • Watch for sleepy cues: Pay attention to your baby’s sleepy cues, such as yawning, rubbing their eyes, or becoming less active.

    • Avoid overstimulation: Avoid stimulating activities or exposing your baby to screens before bedtime, as this can interfere with their sleep.

    Baby Development and Milestones

    As your baby grows and develops, it’s essential to monitor their progress and celebrate their milestones. Here are some tips for tracking your baby’s development:

    • Keep a baby journal: Writing down your baby’s milestones and progress can help you track their development and identify any potential issues.

    • Schedule regular check-ups: Regular check-ups with your pediatrician can help you stay on top of your baby’s development and address any concerns.

    • Provide opportunities for learning: Provide your baby with opportunities for learning and exploration, such as reading, singing, and playing with toys.

    • Be patient: Every baby develops at their own pace, so be patient and don’t compare your baby to others.

    Safety and Emergency Preparedness

    As a parent, it’s essential to be prepared for emergencies and take steps to ensure your baby’s safety. Here are some tips for safety and emergency preparedness:

    • Install safety gates: Install safety gates at the top and bottom of stairs to prevent falls.

    • Secure furniture and appliances: Secure furniture and appliances to prevent tip-overs and other accidents.

    • Keep emergency numbers handy: Keep emergency numbers, such as the poison control hotline, handy in case of an emergency.

    • Take a first aid class: Take a first aid class to learn how to respond to common childhood injuries and illnesses.

    Building a Support Network

    As a new parent, it’s essential to build a support network of family, friends, and other parents. Here are some tips for building a support network:

    • Join a parenting group: Join a parenting group or online community to connect with other parents and get support.

    • Attend parenting classes: Attend parenting classes or workshops to learn new skills and connect with other parents.

    • Reach out to family and friends: Don’t be afraid to reach out to family and friends for support and help when you need it.

    • Take breaks: Take breaks and practice self-care to avoid burnout and maintain your mental health.

    Conclusion

    Parenting is a journey that is both rewarding and challenging. By following these essential tips, you can navigate the ups and downs of parenthood with confidence. Remember to prioritize self-care, build a support network, and stay flexible. With time and practice, you’ll become a confident and capable parent, and you’ll be able to provide your baby with the love, care, and support they need to thrive.

    FAQs

    Q: How often should I feed my baby?
    A: The frequency of feedings will depend on your baby’s age and individual needs. Generally, newborns need to be fed every 2-3 hours, while older babies can go longer between feedings.
    Q: How can I get my baby to sleep through the night?
    A: Establishing a bedtime routine, creating a sleep-friendly environment, and watching for sleepy cues can help your baby sleep through the night.
    Q: What are some common baby milestones?
    A: Common baby milestones include rolling over, sitting up, crawling, and walking. Every baby develops at their own pace, so be patient and don’t compare your baby to others.
    Q: How can I keep my baby safe?
    A: Installing safety gates, securing furniture and appliances, and keeping emergency numbers handy can help keep your baby safe.
    Q: How can I build a support network as a new parent?
    A: Joining a parenting group, attending parenting classes, and reaching out to family and friends can help you build a support network and get the help you need as a new parent.

  • Diverticular disease done differently | Dietitian Connection

    Diverticular disease done differently | Dietitian Connection


    Diverticular disease is common yet remains one of the most misunderstood areas of gastrointestinal nutrition.

    In this episode, Advanced APD Katherine Healy joins us to unpack the latest evidence and bring clarity to the management of diverticular disease. From acute flare-ups to prevention, Katherine shares how to move beyond outdated advice and deliver patient-centred, evidence-based care.

    Hosted by Bec Sparrowhawk

    Biography

    Katherine Healy is an Advanced Accredited Practising Dietitian with over 14 years’ experience across the full spectrum of gastrointestinal disorders. Beginning her career as a microbiological scientist, she blends her love of science and food to deliver evidence-based, patient-centred care. Her research with Monash University explored enzyme therapy in low FODMAP diets, and she now leads pioneering dietitian-led gastroenterology clinics at Northern Health, transforming how dietitians contribute to GI care.


    In this episode, we discuss:

    • The evolving understanding of diverticular disease and its causes
    • Evidence-based nutrition strategies from flare-up to recovery
    • How to debunk myths around historical nutrition advice
    • Practical communication tools to empower patients

    Additional resources

    Can connect with Katherine via email on [email protected]

    For further reading

     

    The content, products and/or services referred to in this podcast are intended for Health Care Professionals only and are not, and are not intended to be, medical advice, which should be tailored to your individual circumstances. The content is for your information only, and we advise that you exercise your own judgement before deciding to use the information provided. Professional medical advice should be obtained before taking action. The reference to particular products and/or services in this episode does not constitute any form of endorsement. Please see  here  for terms and conditions.


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  • Boost Your Brain with Bioidentical Hormone Pellet Therapy

    Boost Your Brain with Bioidentical Hormone Pellet Therapy

    Most people associate the sex hormones with puberty and reproduction. But estrogen, testosterone, and progesterone serve a much greater purpose in human health.

    Numerous studies demonstrate how the sex hormones act like a master switch for every organ and tissue of the body, regulating cognitive function, mood, sleep, and all the neurotransmitters. In fact, brain health hinges completely on hormonal balance.

    Neuroscientific researchers have identified thousands of receptors in various brain regions for testosterone, progesterone, and estrogen. These hormones manage the flow of the “feel good” biochemical messengers, including serotonin, dopamine, oxytocin, and endorphins. The neurotransmitters, or “happiness hormones,” signal every brain cell to perform its specific job.

    Sex hormones regulate brain functions through neurotransmitters. (Illustration by Andrade Design, California/Andradedesign.com)

    As people age, hormonal imbalances can result in cognitive disorders, neurodegenerative diseases, memory loss, mental health conditions, sleep disruption, and neurotransmitter imbalances that often lead to dementia and depression.

    Think of the sex hormones like a remote-control device influencing every thought, movement, behavior, action, and emotion. If the buttons don’t operate, neither will the main screen, and the hormones go haywire. This, in turn, can deteriorate brain health and lead to Alzheimer’s (AD, especially in women as their hormone levels drop when entering menopause.

    According to a 2023 Columbia University Irving Medical Center study, a woman’s risk for developing AD is one in five versus one in ten for a man. The Alzheimer’s Society reports that more than 65 percent of AD patients are women over 45.

    Numerous studies dating over 30 years provide scientific proof for the role of estrogen, progesterone, and testosterone replacement therapy in preventing AD and other neurodegenerative conditions. A 2024 collaboration concluded: “Multiple lines of evidence suggest that loss of estrogens in the aging brains of both women and men may play a significant role in the cognitive decline associated with AD.”

    While it’s no secret that hormones protect the brain, doubt and confusion prevail among some researchers who still question the role and use of hormones in cognitive well-being. Few identify the difference between synthetic hormones and the natural bioidentical kind, similar to those produced by the body.

    Unlike pellets, pharmaceutical hormone pills, patches, creams, gels, and sublinguals result in rollercoaster surges that lack the efficacy of pellets to sustain the 24-7 support that neurotransmitters require.

    Further research shows that the hormone delivery method makes all the difference, with subcutaneous pellets maintaining the optimal physiological hormone levels necessary to protect the brain from AD and other diseases.

    A 2025 report in the New York Times, “Sex Hormones Are Brain Hormones. What Does This Mean for Treating Brain Diseases?” states: “A growing understanding of how reproductive hormones sculpt the brain could transform the management of neurological conditions.”

    Despite all the reports and evidence, why are scientists still struggling to correlate hormones and the brain?

    One visionary medical team already connected the dots over 30 years ago, pioneering a safe, effective method for body and brain health. CarolAnn Tutera, president and CEO of SottoPelle®/Tutera Medical®, co-founded the company with her late husband, Dr. Gino Tutera, a medical pioneer renowned for his groundbreaking innovations using bioidentical hormone pellets.

    Backed by 87 years of scientific research and slipped under the skin, subcutaneous pellets demonstrate the greatest efficacy in penetrating the blood-brain barrier for consistent hormone distribution.

    The Tuteras began using pellet therapy over a decade ago to treat patients with Parkinson’s, Alzheimer’s, and other neurodegenerative symptoms, including former NFL players with concussions.

    Now, CarolAnn continues this medical legacy by collaborating with neuroscientific researchers at the Amen Clinics for a new study tracking how pellet therapy may improve brain health and prevent debilitating diseases.

    Learn more: https://www.sottopelletherapy.com/hormone-therapy-brain-mental-health/

    See also: Bioidentical Pellet Therapy: A Safe Solution for Menopausal Symptoms

    Always consult your physician before beginning any treatment program.

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  • 10 Proven Ways to Overcome Workout Fatigue and Boost Energy for Your Next Gym Session (Target keywords: workout fatigue, boost energy)

    10 Proven Ways to Overcome Workout Fatigue and Boost Energy for Your Next Gym Session (Target keywords: workout fatigue, boost energy)

    Workout fatigue – the arch-nemesis of every fitness enthusiast. It’s that feeling of utter exhaustion and lethargy that hits after a tough gym session, making it a struggle to get out of bed for the next workout. But, what if she could overcome workout fatigue and boost energy for her next gym session? Sounds like a dream come true, right? Well, it’s not just a pipe dream; with the right strategies, she can bid farewell to workout fatigue and hello to a more energetic and productive fitness routine.

    ### Understanding Workout Fatigue

    Before diving into the solutions, it’s essential to understand what causes workout fatigue in the first place. Workout fatigue is a common phenomenon that occurs when the body is pushed beyond its limits, resulting in a depletion of energy stores, inflammation, and muscle damage. This can be due to a variety of factors, including overtraining, poor nutrition, inadequate sleep, and stress. When the body is not given sufficient time to recover, it can lead to a vicious cycle of fatigue, decreased performance, and increased risk of injury.

    ### 1. Listen to Your Body and Rest

    The first step to overcoming workout fatigue is to listen to your body and give it the rest it needs. This means taking rest days as seriously as workout days. When you’re feeling fatigued, it’s essential to take a step back, assess your routine, and make adjustments as needed. This might mean reducing the frequency or intensity of your workouts, or incorporating more low-impact activities like yoga or stretching. By allowing your body time to recover, you’ll be able to come back stronger and more energized for your next gym session.

    ### 2. Fuel Your Body with the Right Nutrition

    What you eat plays a significant role in your energy levels and overall performance. A well-balanced diet that includes plenty of protein, complex carbohydrates, and healthy fats can help boost energy and reduce workout fatigue. Foods rich in iron, such as spinach and lean meats, can help combat fatigue, while foods high in antioxidants, like berries and nuts, can help reduce inflammation. Additionally, staying hydrated by drinking plenty of water throughout the day is crucial for maintaining energy levels and supporting physical performance.

    ### 3. Get Enough Sleep

    Sleep is the unsung hero of fitness. During sleep, your body repairs and rebuilds muscle tissue, replenishes energy stores, and regulates hormones. Aim for 7-9 hours of sleep each night to help your body recover from the physical demands of exercise. Establishing a consistent sleep schedule, avoiding caffeine and electronics before bedtime, and creating a relaxing sleep environment can all help improve the quality of your sleep. By prioritizing sleep, you’ll be able to wake up feeling refreshed, revitalized, and ready to tackle your next workout.

    ### 4. Incorporate Energy-Boosting Supplements

    While a well-balanced diet should always be the primary source of nutrition, certain supplements can help boost energy and reduce workout fatigue. Branched-Chain Amino Acids (BCAAs), for example, can help reduce muscle soreness and fatigue, while beta-alanine can increase muscle carnosine levels, delaying the onset of fatigue. Other supplements like creatine, CoQ10, and iron can also help improve energy production and reduce fatigue. However, it’s essential to consult with a healthcare professional before adding any new supplements to your routine.

    ### 5. Try Active Recovery Techniques

    Active recovery techniques, such as foam rolling, self-myofascial release, and compression garments, can help reduce muscle soreness and improve circulation. These techniques can be especially helpful after intense workouts, as they can help promote blood flow and reduce inflammation. By incorporating active recovery techniques into your routine, you’ll be able to reduce workout fatigue and improve your overall performance.

    ### 6. Mix Up Your Routine

    Doing the same workout routine day in and day out can lead to mental and physical fatigue. Mix things up by trying new exercises, taking a different class, or working out outdoors. Novelty can be a powerful motivator, and changing your routine can help keep you engaged and excited about your workouts. Additionally, incorporating variety into your routine can help reduce the risk of overuse injuries and prevent plateaus.

    ### 7. Find a Workout Buddy

    Having a workout buddy can be a great motivator and help you push through even the toughest of workouts. When you’re feeling fatigued, having someone to hold you accountable and provide support can make all the difference. Plus, exercising with a friend can be a great way to socialize and make workouts more enjoyable. By finding a workout buddy, you’ll be able to stay motivated, boost energy, and overcome workout fatigue.

    ### 8. Get Moving in the Morning

    Starting your day with a morning workout can be a great way to boost energy and set a positive tone for the rest of the day. Morning workouts can help increase alertness, improve mental clarity, and enhance overall physical performance. Plus, getting your workout out of the way in the morning can help reduce stress and increase feelings of accomplishment. By incorporating a morning workout into your routine, you’ll be able to boost energy and overcome workout fatigue.

    ### 9. Try Mind-Body Exercises

    Mind-body exercises, such as meditation and deep breathing, can help reduce stress and anxiety, which are common contributors to workout fatigue. These exercises can help calm the mind, reduce inflammation, and promote relaxation. By incorporating mind-body exercises into your routine, you’ll be able to reduce workout fatigue, improve mental clarity, and enhance overall well-being.

    ### 10. Get Enough Vitamin D

    Vitamin D is an essential nutrient that plays a critical role in energy production and muscle function. Low levels of vitamin D have been linked to fatigue, muscle weakness, and decreased athletic performance. Spending time outdoors, taking vitamin D supplements, or consuming vitamin D-rich foods like fatty fish and fortified dairy products can help boost energy and reduce workout fatigue. By prioritizing vitamin D, you’ll be able to maintain optimal energy levels and support overall physical performance.

    In conclusion, overcoming workout fatigue and boosting energy is within reach. By listening to your body, fueling your body with the right nutrition, getting enough sleep, incorporating energy-boosting supplements, trying active recovery techniques, mixing up your routine, finding a workout buddy, getting moving in the morning, trying mind-body exercises, and getting enough vitamin D, you’ll be able to say goodbye to workout fatigue and hello to a more energetic and productive fitness routine.

    ### FAQs

    Q: What are the most common causes of workout fatigue?
    A: The most common causes of workout fatigue include overtraining, poor nutrition, inadequate sleep, and stress.

    Q: How can I reduce muscle soreness and fatigue after a workout?
    A: Incorporating active recovery techniques, such as foam rolling and self-myofascial release, can help reduce muscle soreness and fatigue.

    Q: What supplements can help boost energy and reduce workout fatigue?
    A: Supplements like BCAAs, beta-alanine, creatine, CoQ10, and iron can help boost energy and reduce workout fatigue.

    Q: How much sleep do I need to help my body recover from exercise?
    A: Aim for 7-9 hours of sleep each night to help your body recover from the physical demands of exercise.

    Q: Can workout fatigue be a sign of an underlying medical condition?
    A: Yes, workout fatigue can be a sign of an underlying medical condition, such as anemia, hypothyroidism, or chronic fatigue syndrome. If you’re experiencing persistent fatigue, it’s essential to consult with a healthcare professional to rule out any underlying conditions.
    10-proven-ways-to-overcome-workout-fatigue-and-boost-energy-for-your-next-gym-session-target-keywords-workout-fatigue-boost-energy

  • From £100,000 House to £20 Million Empire

    From £100,000 House to £20 Million Empire

    When Samuel Leeds left school at seventeen with no qualifications and £50 in his pocket, no one could have predicted that within a decade he would build a £20 million property portfolio.

    His journey began in 2009 with a £100,000 house in the West Midlands. Using creative financing, he turned it into a house share that still earns him rent today.

    “That first deal changed everything,” he says. “It gave me confidence. I realised I didn’t have to work for someone else. I could build something myself.”

    Leeds’s career is a story of constant reinvention. From small buy-to-lets to lease options, HMOs, and finally large developments and hotels, each stage brought new challenges.

    He openly shares his failures, including the costly renovation of Ribbesford House, a Grade II* listed castle that taught him about resilience and planning battles. “That project nearly broke me,” he admits. “But it also made me sharper.”

    Today, his portfolio includes multiple hotels, developments, and long-term social housing projects. He mentors thousands of investors through his academy, teaching them the creative methods that allowed him to build wealth without large savings.

    “People think property is about buildings,” he says. “It’s really about people and persistence. If you help enough people, the money follows.”

    His story has been featured by outlets including GB News and TalkTV, and his book Buy Low Rent High remains a bestseller among new investors.

    For young entrepreneurs looking for proof that financial freedom is still possible, Leeds’s story stands as one of the most compelling in Britain today.



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  • Chronic Kidney Disease, Diabetes, and Heart Disease | Chronic Kidney Disease

    Chronic Kidney Disease, Diabetes, and Heart Disease | Chronic Kidney Disease

    About CKD, diabetes, and heart disease

    The relationship between CKD, diabetes, and heart disease is one example of the ways our organs are connected. When one organ isn’t working properly, it can put stress on other organs, causing them to stop working properly as well.

    Your body uses a hormone called insulin that moves sugars from the blood and into your body’s cells for energy. If someone has diabetes, they either don’t make enough insulin or can’t use the insulin well.

    If someone has CKD, their kidneys don’t filter out toxins and waste from their blood as well as they should.

    Heart disease refers to several types of heart conditions. The most common condition, coronary artery disease, leads to changes in blood flow to the heart. This can cause a heart attack.

    Make the connection

    So how are these three conditions connected? Risk factors for each condition are similar and include:

    • High blood sugar.
    • High blood pressure.
    • Family history.
    • Obesity.
    • Unhealthy diet.
    • Physical inactivity.

    High blood sugar can slowly damage the kidneys. Over time, they may stop filtering blood as well as they should, leading to CKD. Approximately 1 in 3 U.S. adults with diabetes has CKD.

    When the kidneys don’t work well, it puts stress on the heart. When someone has CKD, their heart needs to pump harder to get blood to the kidneys. This can lead to heart disease, the leading cause of death in the United States. Change in blood pressure is also a CKD complication that can lead to heart disease.

    Tips to prevent or manage all three

    The good news is that you can manage or prevent CKD, diabetes, and heart disease all at once. These five tips can help you get started:

    Get active

    Being active can help prevent or manage CKD, diabetes, and heart disease. Find an activity you like, start small, and get moving!

    Choose healthy foods and drinks

    This is an important way to give your body the fuel it needs to function properly. Adding more fruits and veggies to your plate can also help you keep a healthy weight. This is a great way to prevent or manage CKD, diabetes and heart disease.

    Quit smoking

    Quitting is one of the best things you can do for your health. It’ll help you prevent CKD, type 2 diabetes, and heart disease. It also helps to improve any of these conditions if you have them. You don’t have to do it alone! For support, visit I’m Ready To Quit.

    Find out your risk for prediabetes

    Know where you stand by taking this 1-minute prediabetes risk test. If your risk is high, talk to your doctor about taking action to prevent or delay type 2 diabetes. The lifestyle change program through CDC’s National Diabetes Prevention Program can help you build the healthy habits you need to succeed.

    Get your annual flu shot

    People with chronic diseases are more likely to have health complications if they catch the flu. These complications can worsen an existing condition and can even be fatal.

    Protect your heart if you have CKD

    Over time, CKD often gets worse and can lead to kidney failure. People with kidney failure will need regular dialysis (a treatment that filters the blood) or a kidney transplant to survive.

    Heart disease is the most common cause of death for someone on dialysis. When your kidneys don’t function properly, the heart has to work harder to circulate blood. This may lead to high blood pressure and possibly heart disease.

    Tips to help protect your heart and kidneys:

    Choose foods that are healthiest for your heart and your kidneys. Ask your doctor for a referral to a dietitian to understand which foods and drinks are best for you. Learn more about dialysis and a healthy diet.

    Get regular physical activity to help lower your blood pressure and improve your heart health. And remember that moving more doesn’t have to be strenuous. Some great ways to get active are gardening, yoga, or brisk walking around the block. Ask your doctor about which activities are best for you and if there are any you should avoid.

    Manage your weight and blood sugar by changing your diet and activity routine. For extra help, you can work with a dietitian to create an eating plan that works for you and your kidneys.

    Did you know that these conditions are connected?

    When you prevent or manage one condition, you can help prevent or manage all three.

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  • Gene Therapy for Children With Rare ‘Bubble Boy Disease’ Proves Effective After Long-Term Follow-Up

    Gene Therapy for Children With Rare ‘Bubble Boy Disease’ Proves Effective After Long-Term Follow-Up

    The 62 children who were found to have the rare “Bubble Boy disease” as babies and toddlers between 2012 and 2017 still seem cured after long-term follow-up, after being treated with a genetic therapy for severe combined immunodeficiency.

    The results of the trial noted that by 2019, 95 percent of the children, which equates to all but two of the young patients, showed complete immune system reconstruction. And now, years later, long-term follow-up results show that the therapy is still 95 percent effective.

    Treatment for Children With Rare “Bubble Boy Disease”

    In a statement, a pediatric transplant physician at the University of California, Los Angeles, Donald Kohn, MD, said that the durability of immune function, the consistency over time, and the continued safety profile among the children were all encouraging.

    Severe combined immunodeficiency due to adenosine deaminase deficiency (ADA-SCID) is typically caused by mutations in an individual’s ADA gene. This gene is responsible for creating an enzyme that is essential for a person’s immune function, according to Good News Network.

    For kids who have this rare condition, typical daily activities, such as going to school or playing with friends, can result in dangerous, life-threatening infections. If left untreated, ADA-SCID can even be fatal within an infant’s first two years of life.

    SCID suddenly became well-known in America in 1984 because of “the boy in the bubble,” David Vetter. He received a special spacesuit from NASA that allowed him to leave his total medical isolation and see the world. However, despite this suit, the boy passed away due to an infection when he was 12 years old.

    The researchers who led the multi-center program related to the cured children said that the persistence of healthy immune systems and results of long-term follow-up should be taken as signs that the approach could become a standard treatment for individuals with ADA-SCID, Science Media Centre reported.

    An Effective Approach

    The families whose lives were previously defined by the strict isolation of affected individuals are now able to describe ordinary childhood milestones that they would never have dreamed were possible.

    The gene therapy in question is a treatment that was tested by researchers at UCLA in collaboration with institutions in the United Kingdom. It takes a personalized, cell-based approach to correct an individual’s genetic defect.

    The first step in the process is doctors collecting a child’s hematopoietic stem cells from their bone marrow or blood. Then, a laboratory team uses a modified viral vector to deliver a healthy copy of the ADA gene into those stem cells. Finally, those corrected stem cells are returned to the patient, where they then engraft and produce a continual supply of functional immune cells, as per the Valley Vanguard Online.



    Originally published on parentherald.com

    © {{Year}} ParentHerald.com All rights reserved. Do not reproduce without permission.

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  • weight-loss-cookbook

    weight-loss-cookbook

    Product Name: weight-loss-cookbook

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