Tag: treatment

  • Where To Get Huntington’s Disease Treatment? Hope Flows As Doctors Claim First Patient Cured From Neuro Illness

    Where To Get Huntington’s Disease Treatment? Hope Flows As Doctors Claim First Patient Cured From Neuro Illness

    In a groundbreaking development, researchers in the UK have reported the first-ever successful treatment for Huntington’s disease, a hereditary neurodegenerative disorder previously deemed incurable. The experimental gene therapy, known as AMT-130, slowed disease progression by 75% over three years, offering renewed hope to patients and families affected by the condition.

    What Is Huntington’s Disease?

    Huntington’s disease is a progressive neurological disorder caused by a mutation in the HTT gene, leading to the production of a toxic protein that damages brain cells. Symptoms typically manifest in mid-adulthood and include motor dysfunction, cognitive decline, and psychiatric disturbances. The disease is fatal, with patients often succumbing within 15–20 years of symptom onset.

    The Breakthrough Treatment

    Led by Professor Sarah Tabrizi at University College London (UCL), the pioneering clinical trial utilised an innovative gene therapy approach. The treatment involves a one-time surgical procedure lasting up to 20 hours, during which a specially engineered, harmless virus is infused directly into the brain. This virus carries a DNA strand designed to deactivate the mutant huntingtin protein responsible for the disease.

    The results have been nothing short of remarkable. According to a press release from UCL, patients who underwent the treatment experienced a 75% reduction in the expected progression of the disease over a three-year period. Instead of the expected rapid decline, these patients maintained neurological function, effectively gaining years of quality life.

    Expert Insights

    Professor Tabrizi expressed her astonishment at the results, stating, ‘We never in our wildest dreams would have expected a 75% slowing of clinical progression.’ She emphasised that this breakthrough could pave the way for earlier interventions, potentially preventing the onset of symptoms altogether.

    Where to Access Huntington’s Disease Treatment in the UK

    For individuals seeking treatment or support for Huntington’s disease, the UK offers several renowned centres specialising in diagnosis, care, and research:

    • University College London (UCL) Institute of Neurology: A leading research and clinical centre focusing on Huntington’s disease, offering multidisciplinary care and conducting pioneering clinical trials.
    • Cardiff University Huntington’s Disease Centre: A prominent centre dedicated to research and coordination of Huntington’s disease studies across South Wales.
    • Royal Hospital for Neuro-disability: Specialises in providing care and support for patients with complex needs due to Huntington’s disease.
    • Guy’s and St Thomas’ NHS Foundation Trust: Offers follow-up services for individuals diagnosed with Huntington’s disease, including participation in clinical trials.

    These institutions are at the forefront of Huntington’s disease care and research, providing essential services to patients and families affected by the condition.

    Global Implications

    Approximately 6,000 to 10,000 individuals in the UK are affected by Huntington’s disease, with many more at risk due to family history. The success of this gene therapy trial has the potential to revolutionise treatment approaches globally.

    Biotechnology company UniQure plans to seek approval for the therapy in the United States, signalling a new era in the fight against this devastating disorder.

    Looking Ahead

    While gene therapy presents a promising avenue for treatment, the procedure remains complex and expensive. As the medical community continues to assess its long-term efficacy and accessibility, this breakthrough stands as a powerful testament to scientific innovation and its potential to transform lives.

    Originally published on IBTimes UK

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  • New Hodgkin’s Lymphoma Treatment Boosts Fertility Preservation Without Sacrificing Survival

    New Hodgkin’s Lymphoma Treatment Boosts Fertility Preservation Without Sacrificing Survival

    Young adults diagnosed with advanced Hodgkin’s lymphoma may no longer have to choose between survival and future parenthood. A major international study, published in The Lancet Oncology, shows that a new chemotherapy regimen, BrECADD, significantly improves fertility outcomes compared to the long-used eBEACOPP protocol — without compromising recovery rates. Led by researchers from University Hospital Cologne and the German Hodgkin Study Group (GHSG), the findings are poised to shift standard treatment guidelines for younger patients hoping to have children after cancer.

    The results were published in The Lancet Oncology under the title “Fertility in patients with advanced-stage classic Hodgkin lymphoma treated with BrECADD versus eBEACOPP: a secondary analysis of the multicentre, randomised, parallel, open-label, phase 3 HD21 Trial.”

    A Fertility-Friendly Option for Young Cancer Patients

    Hodgkin’s lymphoma, a cancer of the lymphatic system, is one of the most common cancers affecting adolescents and young adults. While current therapies are effective in achieving remission, they often come at a high cost: permanent infertility, particularly for male patients.

    The HD21 trial compared two treatments: the standard eBEACOPP regimen and the newer, experimental BrECADD protocol. Among more than 1,500 participants across nine countries, those treated with BrECADD showed significantly better hormonal recovery three years after treatment.

    Specifically, 95% of women and 86% of men in the BrECADD group had regained normal hormone levels—compared to just 73% of women and 40% of men in the eBEACOPP group. The study also recorded higher numbers of pregnancies and births among those who received BrECADD.

    “For young adults with Hodgkin’s lymphoma, BrECADD offers a better chance at building a family after beating cancer—without compromising survival,” said Dr. Justin Ferdinandus, Study Physician with the GHSG and first author of the study. “It’s a win-win.”

    A New Standard of Care

    BrECADD is already being adopted as the new standard first-line treatment at University Hospital Cologne and has been integrated into the current Onkopedia guideline for treating Hodgkin’s lymphoma in patients who desire fertility preservation.

    “The HD21 study is fundamentally changing clinical practice,” said Dr. Karolin Behringer, Study Physician and senior author of the paper. “Our data clearly support BrECADD as the preferred option for younger patients—especially those who want children in the future.”

    The study tracked hormone recovery through blood serum levels of follicle-stimulating hormone (FSH), a key marker of fertility in both men and women. Researchers also collected data on actual pregnancies and live births, providing real-world evidence of BrECADD’s long-term benefits beyond the lab.

    Backed by Global Collaboration

    The HD21 trial was a randomized, phase III clinical study involving 233 medical centers in nine countries, encompassing patients up to age 60. The study was supported by Takeda Oncology and represents one of the most comprehensive efforts to evaluate fertility outcomes after cancer treatment.

    “This marks a pivotal moment in oncology and survivorship care,” said Dr. Ferdinandus. “We’re not just saving lives—we’re helping patients live the kind of life they dreamed about before cancer.”

    What This Means for Patients

    The findings are particularly meaningful for adolescent and young adult (AYA) cancer patients, who often face difficult decisions about fertility preservation at the time of diagnosis. With BrECADD, fewer may need to resort to invasive or costly fertility preservation procedures before starting treatment.

    For men especially, the study indicates a substantial increase in the likelihood of fathering biological children post-treatment—an area where eBEACOPP was notably limited.

    The researchers hope these findings will encourage oncologists worldwide to consider BrECADD as a frontline option for Hodgkin’s lymphoma in fertility-conscious patients.

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  • Democratic Veterans Could Be Refused Treatment Under Trump’s New Rules for VA Hospitals: Report

    Democratic Veterans Could Be Refused Treatment Under Trump’s New Rules for VA Hospitals: Report

    New guidelines implemented under an executive order by President Donald Trump now allow VA hospital staff to refuse healthcare to veterans based on political affiliation and marital status, prompting concerns that Democratic and unmarried veterans may be denied treatment.

    On January 30, Trump signed an executive order titled “Defending Women from Gender Ideology Extremism and Restoring Biological Truth to the Federal Government.” While its primary aim was to curtail federal protections for transgender individuals, the order also triggered sweeping changes within the Department of Veterans Affairs (VA), according to the Guardian.

    The VA, which serves over 9 million veterans across more than 170 hospitals and 1,000 clinics, revised its internal bylaws to strip longstanding protections against discrimination based on political party, marital status, sexual orientation and national origin.

    The updated policies allow doctors, psychologists, dentists and other healthcare workers at VA hospitals to refuse treatment to veterans based on characteristics not explicitly protected by federal law. While veterans are still legally entitled to care, there is now no rule preventing staff from declining service to individuals based on their political beliefs or whether they are unmarried.

    Internal documents reviewed by the outlet confirm that the changes are already in effect at some VA centers. The VA’s press secretary confirmed the revisions were made to align with Trump’s executive order but did not clarify what federal law required such shifts.

    The new rules have drawn sharp criticism from medical experts and ethics professionals. Dr. Kenneth Kizer, the VA’s top health official, warned the policy could allow providers to deny care to patients based on rape allegations, political activity or substance use. Dr. Arthur Caplan of NYU’s Grossman School of Medicine called the changes “unethical” and “an effort to exert political control over the VA medical staff.”

    Originally published on Latin Times

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  • Knee Stem Cell Injection Gains Attention as an Innovative Treatment

    Knee Stem Cell Injection Gains Attention as an Innovative Treatment

    Autologous Bone Marrow Stem Cell Therapy (BMAC무릎줄기세포주사) for the knee has recently gained recognition as an innovative medical treatment, showing significant effectiveness in treating knee osteoarthritis.

    Eight studies on the BMAC (무릎줄기세포주사) injection, which was officially approved as a new medical technology in South Korea last year, have demonstrated its effectiveness in alleviating knee osteoarthritis pain. In cases ranging from early to mid-stage arthritis, 94.4% of patients experienced considerable pain relief.

    The typical treatment process for knee osteoarthritis begins with non-surgical pain management methods. As the condition progresses, total knee replacement surgery is often required. Because effective pain control can significantly delay the need for surgery, continuous research has been conducted to develop new therapies—among which BMAC injections stand out.

    Previously, corticosteroid injections were commonly prescribed to manage knee arthritis pain. However, recent studies have revealed that steroid injections may actually accelerate joint degeneration.

    MRI scans of arthritis patients showed that those who received steroid injections experienced faster deterioration of cartilage and surrounding tissues.

    Researchers warn that while steroid injections may provide short-term pain relief, they can promote long-term damage to knee tissue. In particular, increased cartilage degeneration and inflammation were observed.

    As a result, medical experts are now urging patients who have been prescribed steroid injections for knee arthritis pain to consider alternative, safer, and more effective treatment options such as BMAC (무릎줄기세포주사) therapy.

    Dr. Yeong-Seok Lee, Director of Saint Luke Hospital, stated, “If knee pain is severe enough to interfere with daily life, it may indicate that the condition has already progressed significantly. It is crucial to seek a specialist’s diagnosis as early as possible.”

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  • California Father Battling Lung Cancer Denied Coverage for ‘Last Option’ Treatment, Family Says

    California Father Battling Lung Cancer Denied Coverage for ‘Last Option’ Treatment, Family Says

    A California man battling stage 4 lung cancer was denied insurance coverage for a potentially life-saving double lung transplant just as he was preparing to fly to Chicago for the procedure, his family says.

    Deron Wells, a 59-year-old husband and father of three, had been medically approved for a rare clinical trial lung transplant at Northwestern Medicine in Illinois, according to ABC 7.

    Cigna, his insurer, had initially signed off on the necessary procedures and transport from UCLA Santa Monica Medical Center, where he had been receiving care. But on the day of his scheduled transfer, Cigna reversed course, denying coverage for both the transplant and the out-of-state medical transfer.

    “The last option we have is for us to take him to Northwestern, period. I hope Cigna really understands the seriousness of the situation. We’re not just a number. We are talking about his life,” Janet Savarimuthu, the man’s wife, told the outlet.

    Lung transplants are not typically considered standard treatment for cancer, which Cigna cited in its statement defending the denial, claiming their coverage guidelines are based on national clinical standards.

    Wells’ family and friends launched an appeal and a public campaign in an effort to pressure the insurer to reconsider. A response to the appeal is expected by Thursday.

    The man’s GoFundMe has raised more than $37,000 as of Friday morning.

    Originally published on Latin Times

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  • CDC Warns Travelers Of Deadly Virus That Has No Approved Vaccines Or Treatment

    CDC Warns Travelers Of Deadly Virus That Has No Approved Vaccines Or Treatment

    The U.S. Centers for Disease Control and Prevention (CDC) has issued a health advisory warning travelers about an Ebola outbreak in Uganda caused by the deadly Sudan virus, which has no approved vaccines or treatments.

    The CDC raised the alert to Level 2, urging travelers to “Practice Enhanced Precautions,” according to a Health Alert Network advisory issued Thursday.

    The current outbreak of Sudan Virus Disease (SVD) has been reported in the Kampala, Mbale, and Wakiso regions of Uganda. Since 2000, the country has already experienced seven outbreaks of the virus.

    The first case of the current outbreak was identified after a male nurse died from the infection on January 29. A second case, identified as the wife of the index patient, has also developed symptoms and tested positive, according to a WHO weekly bulletin issued last week.

    While three of the man’s close contacts have developed symptoms and are in isolation for treatment and testing, a total of 234 contacts have been traced, including 118 linked to medical settings.

    Although there are no direct flights from Uganda to the United States, travelers from or passing through affected areas can enter the U.S. on flights connecting from other countries. Hence the CDC cautions health officials to be on alert and evaluate any patients suspected of having SVD.

    However, the CDC confirmed that “currently, no suspected, probable, or confirmed Ebola cases related to this outbreak have been reported in the United States, or outside of Uganda.”

    An initial investigation suggests the latest outbreak is not linked to the earlier outbreaks and officials suspect a new jump from animals to people.

    “The source of exposure remains unknown, raising concerns about undetected transmission chains or a new zoonotic spillover,” the WHO bulletin stated. Previous outbreaks have shown a case fatality rate ranging from 41% to 70%.

    As part of the “enhanced precautions” to reduce the risk of infection, the CDC recommends people who travel to Uganda avoid contact with sick individuals, their bodily fluids, and items they have touched, including those who have died. They are also advised to refrain from handling wild animals, visiting high-risk areas like caves or healthcare facilities in affected regions, and engaging in burial practices that involve touching the deceased.

    Travelers are asked to watch out for symptoms during the stay and three weeks after returning. Anyone experiencing symptoms is advised to isolate immediately and alert the local healthcare facility. Symptoms include fever, chills, headache, muscle aches, rash, chest pain, sore throat, nausea, vomiting and diarrhea. As the disease progresses, the patients may also develop unexplained bleeding or bruising.

    “Calling ahead before going to a healthcare facility helps the facility prepare for your arrival, including contacting health authorities and taking any precautions needed to protect staff and other patients,” the CDC said.

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  • Remedies And When To Seek Treatment

    Remedies And When To Seek Treatment

    As the winter season sets in, coughs become more common. While some people may experience a persistent cough due to allergies, others might develop a cough from infections. It’s important to know when to manage a cough at home and when to seek professional care, as coughs linked to seasonal changes or irritants like dust and cold air may require different treatment than those caused by a viral or bacterial infection.

    Causes of cough:

    Coughing is the body’s natural defense mechanism, clearing irritants like mucus, smoke, and allergens such as dust, mold, and pollen from the airways. It can be triggered by infections like the flu, COVID-19, or the common cold or due to lung health conditions such as asthma or COPD.

    Severe coughs lasting for longer periods can sometimes be a sign of more severe conditions such as lung cancer, tuberculosis, and cystic fibrosis.

    A short-term cough from choking occurs when food or other obstructions block the airway, affecting breathing. In such cases, immediate medical attention is necessary.

    Types of cough:

    Dry cough– A dry cough feels like a tickling sensation in the throat but doesn’t bring up any mucus. It occurs due to inflammation in the lungs. A dry cough that occurs at night may be caused by mucus dripping from the nose or sinuses, which can irritate the throat. These coughs can last for several weeks or until a cold or flu runs its course. Many people experience dry coughs for weeks after recovering from COVID-19. Acid refluxes can also trigger a dry cough.

    To get relief from a dry cough, using lozenges or cough suppressants can help soothe the throat. Staying hydrated and using a humidifier may also provide some comfort. If the dry cough is due to asthma, or acid reflux issues, you might need to consult a doctor and get the appropriate medications. However, if coughing is accompanied by symptoms such as difficulty breathing, chest tightness, bluish lips, or confusion, it’s important to seek immediate medical attention.

    Wet cough- A wet cough, also known as a productive cough, occurs when mucus builds up in the airways. It can be caused by lung conditions like COPD or bacterial and viral infections. Wet coughs accompanied by wheezing may also signal a more serious health issue, such as congestive heart failure, where the heart struggles to pump blood throughout the body.

    The use of over-the-counter cough and cold medications may help clear the phlegm from the airways. For children, the use of saline nasal drops and honey may help relieve the symptoms. However, if a wet cough persists for more than three weeks, it’s best to consult a doctor.

    Paroxysmal cough- It is characterized by intermittent attacks of violent, uncontrollable coughing leading to pain and difficulty in breathing. Such bouts of severe cough can occur with pertussis or whooping cough. Other common causes are asthma, COPD, pneumonia, and tuberculosis.

    Reducing exposure to possible triggers of asthma and COPD can help relieve symptoms. If the cough is caused by pertussis, treatment with antibiotics is necessary. Early diagnosis and prompt treatment lead to better outcomes.

    Croup cough- Croup occurs when the upper airway becomes inflamed in young children due to a viral infection. This type of cough is characterized by a distinctive barking sound. Other signs of croup in children include difficulty breathing, making high-pitched noises during inhalation, and rapid breathing. In severe cases, the child’s skin may become pale or even bluish, indicating a more serious condition.

    Taking medications for fever, using a humidifier, and staying hydrated can help relieve mild symptoms. However, if symptoms are severe or last longer than 3 to 5 days, seek immediate medical attention. Warning signs include noisy, high-pitched breathing sounds, trouble swallowing or drooling, unusual tiredness or restlessness, rapid breathing, difficulty breathing, or a blue or gray tint around the nose, mouth, or fingernails.

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  • Your Menopause Treatment Tablets Could Affect Heart Health: Here’s What Study Says

    Your Menopause Treatment Tablets Could Affect Heart Health: Here’s What Study Says

    Hormone tablets taken during menopause provide relief from symptoms, but do they have long-term health risks? Researchers have found that hormone replacement therapy (HRT) tablets containing both estrogen and progestogen may increase the risk of heart disease and blood clots in menopausal women.

    During menopause, women’s body goes through a series of changes due to a decrease in female hormones, progesterone, and estrogen resulting in symptoms such as hot flashes, mood swings, night sweats, insomnia, and vaginal dryness. These symptoms are often frustrating, interfering with their daily lives and mental well-being.

    HRT was once commonly prescribed for menopausal symptoms and to reduce the risk of bone loss during this stage. However, recent studies pointing to long-term risks have led to a more cautious approach. It is now recommended only for those where the benefits outweigh the risks. The estimate shows that only 5% of women in the U.S. use it now, a significant drop from about 27% two decades ago.

    The latest study published in The BMJ examined the effects of HRT tablets on heart health based on the route of administration and the combination of hormones used. The study suggests that tablets containing both estrogen and progesterone, such as oral combined continuous, oral combined sequential, oral unopposed estrogen, and transdermal combined therapy, increased the risk of ischemic heart disease and venous thromboembolism (blood clots) in women.

    The researchers also found that the tablet tibolone in particular was linked to a higher risk of heart disease, heart attack, and stroke, but not blood clots. Tibolone is a synthetic hormone that contains estrogen, progesterone, and testosterone.

    “Compared with not starting menopausal hormone therapy, starting oral combined continuous therapy or tibolone was associated with an increased risk of ischemic heart disease,” the news release stated.

    “If 1,000 women started each of these treatments and were observed for a year, we would expect to see seven new cases of venous thromboembolism across all groups,” the researchers wrote.

    However, there was no increased risk associated with transdermal treatments such as skin patches, gels, and creams.

    The researchers caution that the study does not prove that HRT causes heart health risks, as the findings are based on observational data. Also, the lack of information on menopausal status and other unmeasured factors, such as smoking and body mass index, may have influenced the results.

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  • Texas Doctors Forced a Miscarrying Woman to Wait Nearly 2 Days Before Receiving Treatment. She Died of a Preventable Infection

    Texas Doctors Forced a Miscarrying Woman to Wait Nearly 2 Days Before Receiving Treatment. She Died of a Preventable Infection

    A woman in Texas reportedly died from a preventable infection because doctors “had to wait until there was no heartbeat,” according to state law, before treating her for a miscarriage at 17 weeks. She left behind a husband and 1-year-old daughter.

    At 17 weeks pregnant, Josseli Barnica was taken to a Houston hospital where doctors told her it was “inevitable” that she would miscarry her son. However, according to ProPublica, they had to wait 40 hours to remove the fetus, leaving her uterus exposed to infection, until there was no heartbeat due to the state’s abortion ban.

    During that time, Barnica prayed she would make it home to her 1-year-old “princess,” but she died the next day with her husband by her side, leaving him to raise his daughter as a single father while most of their family remained in Honduras.

    More than a dozen medical experts, including maternal-fetal medicine specialists, OB-GYNs, and researchers, said Barnica’s death was “preventable.” They also labeled her case as “horrific,” “astounding,” and “egregious,” ProPublica reported.

    Barnica died at HCA Houston Healthcare Northwest, which would not comment directly on her case to ProPublica, but HCA Healthcare stated, “Our responsibility is to be in compliance with applicable state and federal laws and regulations,” adding that physicians exercise their independent judgment.

    Originally published by Latin Times

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  • Is Mindfulness a Treatment for Depression?

    Is Mindfulness a Treatment for Depression?

    Depression is a classic example of what’s referred to today as an invisible illness. When you’re depressed, you may find yourself expending precious energy just so you can appear to the world as if nothing at all is troubling you. 

    This “it’s-work-to-seem-fine” coping mechanism illustrates just one way in which depression complicates your life. Not only are you exhausting yourself pretending to be OK, you may find it hard to rally support from friends, family, and coworkers who only see how well you seem to be functioning. 

    While there is rapidly growing recognition of the very real difficulty and damage caused by depression, the stigma of past decades and centuries lingers. We often still hear the familiar notion that you can just “pull yourself together and get on with it,” as though keeping a “stiff upper lip” should be enough to defeat depression. But strong neurochemical, social, and environmental factors contribute to this very real, physical illness, and successful treatment requires more than maintaining an “upbeat attitude.”

    Depression Is a Chameleon 

    Our ability to recognize and effectively treat depression—which 1 in 14 people will experience in their lifetime—is complicated by the fact that it manifests differently in everyone affected, according to the National Institutes of Health. Anything—your age, your gender, or the stage of your depression—can change what the illness looks like for you, meaning it’s not necessarily simple to get a diagnosis, or even recognize symptoms of depression, whether in yourself or in other people.

    For women, depression is more likely to appear as sadness, worthlessness, and guilt. Hormonal and life cycle-related changes, as in postpartum depression, can make women more susceptible to developing the illness. In fact, women are statistically more likely than men to experience depression. 

    For men, depression often looks like exhaustion, irritability, and sleeping problems. They also lose interest in things they once enjoyed. Men are also more likely to turn to drugs and alcohol, experiment with reckless activity, or become intensely devoted to work in order to distract themselves from their illness.  

    For teens and tweens, depression can look like extended and severe periods of sulking, getting into trouble at school, prolonged irritability, and an intense feeling of being misunderstood. 

    These are by no means the only ways depression can appear. Some people experience short, intense periods of depression, while others feel it as an unmoving cloud over their awareness; for some, it’s linked to difficult life events, while for others it doesn’t go away even when their outward circumstances seem fine. 

    Should You Try Mindfulness for Depression?

    Various treatment options for depression exist, including drug regimens and talk therapies. However, the jury continues to be out on how effective antidepressants are for treating depression. A comprehensive 2018 study conducted by an international research team examined 522 studies, including 116,477 patients, to learn about the effectiveness of 21 antidepressant medications. The researchers discovered that, although nearly all of the drugs were more effective than placebos, their effects were still “modest” in most cases.

    Complicating treatment is the fact that depression is often a chronic condition that tends to relapse, even with medication and talk therapy. According to research, relapse rates range from 50% to as high as 80%.

    Interestingly, when mindfulness is added to the standard depression treatment protocols, relapse rates decline. But it’s unlikely that simply practicing basic mindfulness meditation will ease your depression symptoms. In fact, such an attempt could be supremely unhelpful, notes Julienne Bower, PhD, professor of health psychology at UCLA.

    She tells us that the research showing that mindfulness meditation improves symptoms of depression is, at best, vague. She also notes that it’s really hard to meditate on your own when you’re depressed.

    Zindel Segal, PhD, concurs. The Distinguished Professor of Psychology in Mood Disorders at the University of Toronto, Dr. Segal has pioneered the use of mindfulness meditation for promoting wellness in the area of mood disorders. He was also one of the team who developed Mindfulness-Based Cognitive Therapy (MBCT), a research-backed mindfulness protocol for depressive disorders.

    Chronic Unhappiness?

    “When we talk about depression, and where mindfulness is strong and less strong as a treatment, we have to know what type of depression you have,” says Segal.

    “Don’t consider mindfulness a treatment when you’re dealing with acute depression,” he advises. Depression “shuts down your concentration and disrupts your executive network ability,” which makes practicing mindfulness difficult, says Dr. Segal. Instead, for acute depression, consider seeing a mental health professional for treatment with antidepressants, cognitive behavior therapy, or both. Mindfulness can bolster those treatments, but not replace them.

    Mindfulness-Based Cognitive Therapy, however, was specifically designed to help people who are depressed or chronically unhappy. MBCT is a therapeutic protocol that combines cognitive therapy, which helps people interrupt the disturbing behavior or thought patterns that interfere with their lives, with mindfulness practices that help you learn to develop a healthier relationship to unhelpful thought patterns.

    “Our research looked at specific ways that MBCT helps people work with rumination and worry in ways that are more generous and compassionate,” says Dr. Segal. “This therapy helps you learn to ‘de-center’ and allows you to see your thoughts unfold moment to moment. It helps you to not listen to the messages that depression is sending you.”

    How MBCT Helps

    The goal of MBCT is to help you become familiar with the ways your mind and your thinking patterns contribute to depression, which helps you to develop a new relationship to your depression.

    According to Dr. Segal, many people describe leaving the MBCT training with these two major insights:

    1) Thoughts are not facts.

    2) Depression is not me.

    At first, these points may seem overly simplistic—but when we pay attention to how we are thinking and feeling, over time we become better at spotting the buildup of difficult emotions and thoughts. In that way, we can deal with them more skillfully, instead of just reacting in ways that might not be good for us.

    “Mindfulness practices—focusing on the breath and body, as well as mindful movement and developing greater mindful attention to everyday activities—help us learn to recognize the feelings and patterns of thinking that cause unhappiness,” says Willem Kuyken, PhD, the Ritblat Professor of Mindfulness and Psychological Science at the University of Oxford.  “We learn that thoughts are just thoughts. They are not facts, and we can choose whether to give them power over our minds and hearts. In time they can even help us savor and enjoy all the things that give us pleasure and a sense of accomplishment,” adds Kuyken.

    When it comes to depression that relapses after treatment, he suggests that MBCT has proven to be particularly helpful, if you adhere to the program. The program consists of eight weeks of classes, as well as at-home practices you do on your own for about an hour a day. “Many people [with depression] are trying to turn around very long-standing and ingrained habits of thinking and behaving, and that will take time and effort,” says Dr. Kuyken. He notes that a recent study by Dr. Segal showed that the more a person practices MBCT over time, the greater the benefits for easing depression.

    To find a therapist who has been trained and certified in practicing MBCT, visit accessmbct.com

    If You Need Help

    If you or someone you care for is having suicidal thoughts, these helplines in the US, Canada, and UK offer free, confidential prevention, crisis resources, and support 24/7/365.

    US: Dial 988 to reach the Suicide & Crisis Lifeline.
    988lifeline.org

    Canada: Dial 988 to reach the Suicide Crisis Helpline.
    988.ca

    UK: Dial 116-123 to reach Samaritans.
    samaritans.org

    This article was first published in the April 2020 issue of Mindful magazine.

    The Ultimate Guide to Mindfulness for Sleep 

    Sufficient sleep heals our bodies and minds, but for many reasons sleep doesn’t always come easily. Mindfulness practices and habits can help us fall asleep and stay asleep. Consult our guide to find tips for meditation, movement, and mindfulness practices to ease into sleep. Read More 

    • Mindful Staff
    • July 13, 2023



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