Tag: Fungal

  • Fungal Toxins for Breakfast?

    Fungal Toxins for Breakfast?

    One of the few food contaminants found at higher levels in those eating plant-based diets are mycotoxins, fungal toxins in moldy food ingredients, such as oats.

    In France, exposure to dietary contaminants was compared between vegetarians and meat-eaters, and the results showed that exposures to persistent organic pollutants like PCBs and dioxins were dramatically lower among those eating more plant-based foods. This was due to their avoidance of foods of animal origin, though they did have higher estimated exposure to some mycotoxins, fungal toxins present in moldy food.

    There are many types of mold on the planet, possibly millions, and the vast majority are harmless. However, over the last several years, certain mold toxins, such as aflatoxin and ochratoxin, have been popping up in breakfast cereals. Hundreds of samples were taken off store shelves, and about half were found to be contaminated with ochratoxin, but those store shelves were in Pakistan, which has a sub-tropical climate with monsoons and flash floods, leading to fungal propagation. Similar results have since popped up in Europe, in Serbia, for instance. They’ve also been found in Spain and seen in Portugal. Then, mycotoxins were discovered in breakfast cereals in Canada. What about breakfast cereals sold in the United States?

    Researchers collected 144 samples and, similar to other countries, found that about half contained ochratoxin, but only about 7% exceeded the maximum limit established by the European Commission. What is the significance of finding ochratoxin in U.S. breakfast cereals? In the largest study to date, which included nearly 500 samples of cereal off store shelves across the United States, overall detection rates were about 40%, though only 16 of the samples violated the European standards. All the cereals with ochratoxin were oat-based; however, about 1 in 13 of the oat-based cereal samples tested were contaminated.

    Ochratoxin has become increasingly regulated by many countries to minimize chronic exposure. Shown below and at 2:23 in my video Ochratoxin in Breakfast Cereals are the current regulations for mycotoxins in cereal-based baby foods, for example, worldwide.

    Some countries are very strict, like in the European Union; other countries are less so, and one country in particular has no standards at all. Ochratoxin is not currently regulated at all in the United States.

    What about sticking to organic products? One might expect them to be worse due to the fact that fungicides are not allowed in organic production. However, “mycotoxin concentrations are usually similar or reduced in organic compared with conventional products.” For example, in one of the breakfast cereal studies, researchers found similar contamination, and the same was found for infant foods. It cannot be concluded that organic is better than conventional from a mycotoxin perspective. “Despite no use of fungicides, an organic system appears generally able to maintain mycotoxin contamination at low levels.” But how much is that saying, given how widespread it is? How concerned should we be about the public health effects from “long-term exposure to this potent mycotoxin”?

    If you look at blood samples taken from populations going back decades, sometimes 100% of people turn up positive for ochratoxin circulating in their bloodstream. In some sense, mycotoxins “are unavoidable contaminants of food,” since they are not easy to detect and many of them can remain hidden. And, once foods have become contaminated, mycotoxins aren’t destroyed by cooking. So, are there some foods we should simply try to avoid due to a higher risk of contamination? That’s exactly the question I’m going to address next.

    Doctor’s Note

    This is the first video in a four-part series on mold toxins. Check related posts below for the other three.



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  • Eye Drops Recalled For Possible Fungal Contamination That May Affect Eyesight: FDA Warns

    Eye Drops Recalled For Possible Fungal Contamination That May Affect Eyesight: FDA Warns

    The U.S. Food and Drug Administration (FDA) has sounded the alarm on a nationwide recall of Systane brand eye drops, citing potential fungal contamination that could pose serious risks to eyesight.

    Systane Lubricant Eye Drops Ultra PF, commonly used to temporarily relieve burning and irritation caused by dry eye symptoms, is now at the center of a nationwide recall. The product was distributed to multiple retail stores and online platforms.

    Manufacturer Alcon Laboratories initiated the voluntary recall after a consumer reported foreign material inside a sealed single-use vial, which was later identified as fungal contamination.

    “Fungal contamination of an ophthalmic product is known to potentially cause eye infections. If an infection occurs, it may be vision-threatening, and in very rare cases potentially life-threatening in immunocompromised patients,” the FDA stated in a news release.

    The FDA has confirmed that no adverse events related to the recall have been reported so far. However, individuals experiencing quality issues or adverse reactions after using the product are encouraged to report them through the FDA’s MedWatch Adverse Event Reporting program. Complaints can be submitted online, by downloading and mailing the form, or via fax at 1-800-FDA-0178.

    Each cardboard box of the product contains 25 sterile, single-use vials of lubricant solution for ophthalmic use. “The affected Systane Lubricant Eye Drops Ultra PF, Single Vials On-the-Go, 25 count is limited to lot number 10101, expiration date 2025/09. The product can be identified by the green and pink carton design, the presence of “Systane” and “ULTRA PF” brand names on the front of the carton, and the “25 vials” package size,” the news release stated.

    Consumers who still have the products with them are advised to stop usage immediately and return to the place of purchase for a replacement or refund. Those who experience any issues potentially linked to the use of these eye drops should seek advice from a healthcare provider without delay.

    As Alcon conducts its investigation, a spokesperson told NBC News that “the presence of foreign material appears to be isolated to the single unit returned by a customer.” They emphasized that the recall is being carried out, “out of an abundance of caution to prioritize consumer safety.” Those who have issues with the product can also contact them at 800-241-5999.

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